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Serving leading biopharmaceutical companies globally:

Farmers Insurance
Federal Trade Commission
Queensland Health
Harvard Business School

Generated: November 19, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,137,711

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Summary for Patent: 5,137,711

Title: Paramagnetic DTPA and EDTA alkoxyalkylamide complexes as MRI agents
Abstract:Novel magnetic resonance imaging agents methods utilize complexes of paramagnetic ions with alkoxyalkylamide deriviatives of diethylenetriaminepentaacetic acid ("DTPA") or ethylenediaminetetyraacetic acid ("EDTA"). These novel imaging agents are characterized by excellent NMR image-contrasting properties and by high solubilities in physiological solutions. The complexes are represented by the following formula: ##STR1## wherein A is --CH.sub.2 CH.sub.2 -- or ##STR2## and M.sup.+Z is a paramagnetic ion of an element with an atomic number of 21-29, 42-44 or 58-70, and a valence number, Z, of 2 or 3; R.sup.1 is --O.sup.- or R.sup.3 --N--R.sup.2, R.sup.2 is --(CH.sub.2 CH.sub.2 O).sub.n --R.sup.4, n is 1-10, R.sup.4 is alkyl or aryl, R.sup.3 is H, R.sup.2, alkyl, hydroxy, alkoxy, cycloalkyl or aryl, wherein Z of the R.sup.1 groups are --O.sup.- and the remainder of the R.sup.1 groups are R.sup.2 -N--R.sup.3 groups.
Inventor(s): Weber; Robert W. (Downingtown, PA), Periasamy; Muthunadar P. (Creve Coeur, MO)
Assignee: Mallickrodt Medical, Inc. (St. Louis, MO)
Application Number:07/377,491
Patent Claim Types:
see list of patent claims
Compound; Composition; Dosage form; Use;

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International Patent Family for Patent: 5,137,711

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Germany122007000068► Subscribe
Germany68927173► Subscribe
European Patent Office0425571► Subscribe07C0052France► Subscribe
European Patent Office0425571► Subscribe300299Netherlands► Subscribe
European Patent Office0425571► SubscribeSPC/GB07/052United Kingdom► Subscribe
European Patent Office0425571► Subscribe2007C/064Belgium► Subscribe
Canada1339821► Subscribe
Brazil1101072► Subscribe
Australia3988589► Subscribe
Australia650615► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Federal Trade Commission
Cantor Fitzgerald

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