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|Abstract:||Novel antiprotozoal naphthoquinones having the general formula ##STR1## (wherein either R.sup.1 is hydrogen and R.sup.2 is selected from C.sub.1-6 alkoxy, aralkoxy, C.sub.1-6 alkyl-C.sub.1-6 alkoxy, phenyl substituted by one or two groups selected from halogen and C.sub.1-6 alkyl, halogen and perhalo-C.sub.1-6 alkyl; or R.sup.1 and R.sup.2 are both C.sub.1-6 alkyl or phenyl; and n is 0 or 1) and salt thereof. The compounds of formula (I) are useful for the treatment or prophylaxis of protozoal diseases including malaria, theileriosis and coccidiosis. Various processes for preparing compounds of formula (I) are described.|
|Inventor(s):||Hudson; Alan T. (Sevenoaks, GB), Randall; Anthony W. (Hayes, GB)|
|Assignee:||Burroughs Wellcome Co. (Research Triangle Park, NC)|
Patent Claim Types:|
see list of patent claims
|Compound; Use; Dosage form; Composition;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|United Kingdom||8310141||Apr 14, 1983|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|European Patent Office||0123238||<subscribe>||95C0009||Belgium||<subscribe>|
| This preview shows a limited data set|
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