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Serving leading biopharmaceutical companies globally:

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Generated: January 17, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,978,672

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Summary for Patent: 4,978,672
Title: Alpha-heterocyclc substituted tolunitriles
Abstract:The invention is concerned with aromatase inhibiting compounds of formula I ##STR1## wherein R and Ro represent hydrogen or lower alkyl; or R and Ro located on adjacent carbon atoms and together when combined with the benzene ring to which they are attached form a naphthalene or tetrahydronaphthalene ring; R.sub.1 and R.sub.2 independently represent hydrogen, lower alkyl, (lower alkyl, aryl or aryl-lower alkyl)-thio, lower alkenyl, aryl, aryl-lower alkyl, C.sub.3 -C.sub.6 -cycloalkyl, or C.sub.3 -C.sub.6 -cycloalkyl-lower alkyl; or R.sub.1 and R.sub.2 combined represent lower alkylidene, mono- or di-aryl-lower alkylidene; R.sub.1 and R.sub.2 combined also represent C.sub.4 -C.sub.6 -straight chain alkylene, lower alkyl-substituted straight chain alkylene or ortho-phenylene bridged-C.sub.2 -C.sub.4 -straight chain alkylene, each forming with the carbon atom attached thereto a corresponding optionally substituted or benzo-fused 5, 6 or 7-membered ring; W represents 1-imidazolyl, 1-(1,2,4- or 1,3,4)-triazolyl or 3-pyridyl; or W represents 1-imidazolyl, 1-(1,2,4 or 1,3,4)-triazolyl or 3-pyridyl substituted by lower alkyl; and pharmaceutically acceptable salts thereof.
Inventor(s): Bowman; Robert M. (Summit, NJ), Steele; Ronald E. (Long Valley, NJ), Browne; Leslie (Aesch, CH)
Assignee: Ciba-Geigy Corporation (Ardsley, NY)
Application Number:07/240,862
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 4,978,672

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 4,978,672

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0236940 ➤ Subscribe SPC/GB97/013 United Kingdom ➤ Subscribe
European Patent Office 0236940 ➤ Subscribe 97C0053 Belgium ➤ Subscribe
European Patent Office 0236940 ➤ Subscribe C970011 Netherlands ➤ Subscribe
Spain 2059317 ➤ Subscribe
Finland 870903 ➤ Subscribe
Finland 91857 ➤ Subscribe
Hong Kong 50296 ➤ Subscribe
Algeria 1055 ➤ Subscribe
Denmark 172190 ➤ Subscribe
Czech Republic 279028 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

AstraZeneca
Argus Health
Cipla
Cantor Fitzgerald
Chinese Patent Office
Merck
Boehringer Ingelheim
McKinsey
Federal Trade Commission

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