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Details for Patent: 4,966,891

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Summary for Patent: 4,966,891

Title: Fluorocytidine derivatives
Abstract:The novel 5'-deoxy-5-fluorocytidine derivatives of formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are hydrogen or an easily hydrolyzable radical under physiological conditions, with the proviso that, at least one or R.sup.1, R.sup.2 and R.sup.3 is an easily hydrolyzable radical under physiological conditions, as well as hydrates of solvates of these compounds have antitumor properties. They can be prepared from compounds of formula I, wherein R.sup.1 is hydrogen or an amino-protecting radical and R.sup.2 and R.sup.3 are hydrogen or a hydroxy-protecting radical or taken together are a cyclic hydroxy-protecting radical.
Inventor(s): Fujiu; Morio (Chigasaki, JP), Ishitsuka; Hideo (Yokohama, JP), Miwa; Masanori (Kamakura, JP), Umeda; Isao (Yokohama, JP), Yokose; Kazuteru (Urayasu, JP)
Assignee: Hoffmann-La Roche Inc. (Nutley, NJ)
Application Number:07/268,437
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

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Foreign Priority and PCT Information for Patent: 4,966,891

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
87116926.4Nov 17, 1987

International Patent Family for Patent: 4,966,891

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina247217► Subscribe
Austria124951► Subscribe
Australia2516888► Subscribe
Australia619220► Subscribe
Canada1327358► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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