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Serving leading biopharmaceutical companies globally:

Accenture
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Citi
Cipla
Argus Health
AstraZeneca
Cantor Fitzgerald
Express Scripts
McKesson
Chubb

Generated: February 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,966,891

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Summary for Patent: 4,966,891
Title: Fluorocytidine derivatives
Abstract:The novel 5'-deoxy-5-fluorocytidine derivatives of formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are hydrogen or an easily hydrolyzable radical under physiological conditions, with the proviso that, at least one or R.sup.1, R.sup.2 and R.sup.3 is an easily hydrolyzable radical under physiological conditions, as well as hydrates of solvates of these compounds have antitumor properties. They can be prepared from compounds of formula I, wherein R.sup.1 is hydrogen or an amino-protecting radical and R.sup.2 and R.sup.3 are hydrogen or a hydroxy-protecting radical or taken together are a cyclic hydroxy-protecting radical.
Inventor(s): Fujiu; Morio (Chigasaki, JP), Ishitsuka; Hideo (Yokohama, JP), Miwa; Masanori (Kamakura, JP), Umeda; Isao (Yokohama, JP), Yokose; Kazuteru (Urayasu, JP)
Assignee: Hoffmann-La Roche Inc. (Nutley, NJ)
Application Number:07/268,437
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 4,966,891

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,966,891

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
87116926.4Nov 17, 1987

International Patents Family Members for US Patent 4,966,891

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 247217 ➤ Sign Up
Austria 124951 ➤ Sign Up
Australia 2516888 ➤ Sign Up
Australia 619220 ➤ Sign Up
Canada 1327358 ➤ Sign Up
China 1022688 ➤ Sign Up
China 1033183 ➤ Sign Up
Czechoslovakia 274486 ➤ Sign Up
Czechoslovakia 8807475 ➤ Sign Up
Germany 10199027 ➤ Sign Up
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Teva
Fuji
Covington
Johnson and Johnson
Julphar
Medtronic
Chubb
Harvard Business School
Daiichi Sankyo

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