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Last Updated: October 18, 2021

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Details for Patent: 4,933,360

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Summary for Patent: 4,933,360
Title: Novel chlorthalidone process and product
Abstract:Water-soluble dispersions of chlorthalidone are prepared by a process comprising: (a) forming a solution comprising a water soluble pharmaceutically acceptable polymeric carrier and a C.sub.1 -C.sub.4 alkanol, (b) dissolving chlorthalidone in the solution thus formed, and (c) removing the C.sub.1 -C.sub.4 alkanol from the solution by evaporation, the amount of said carrier being effective to suppress substantially the formation of the alkyl ether by-product from the reaction of chlorthalidone with the C.sub.1 -C.sub.4 alkanol. A preferred water soluble carrier is polyvinylpyrrolidone and a preferred C.sub.1 -C.sub.4 alkanol is methanol.
Inventor(s): Pandit; Nivedita (Middlebury, CT), Horhota; Stephen T. (Brookfield, CT)
Assignee: Boehringer Ingelheim Pharmaceuticals, Inc. (Ridgefield, CT)
Application Number:06/796,467
Patent Claim Types:
see list of patent claims
Process; Formulation; Composition; Dosage form; Use;

Drugs Protected by US Patent 4,933,360

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Boehringer Ingelheim

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