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Generated: August 22, 2017

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Title: Novel chlorthalidone process and product
Abstract:Water-soluble dispersions of chlorthalidone are prepared by a process comprising: (a) forming a solution comprising a water soluble pharmaceutically acceptable polymeric carrier and a C.sub.1 -C.sub.4 alkanol, (b) dissolving chlorthalidone in the solution thus formed, and (c) removing the C.sub.1 -C.sub.4 alkanol from the solution by evaporation, the amount of said carrier being effective to suppress substantially the formation of the alkyl ether by-product from the reaction of chlorthalidone with the C.sub.1 -C.sub.4 alkanol. A preferred water soluble carrier is polyvinylpyrrolidone and a preferred C.sub.1 -C.sub.4 alkanol is methanol.
Inventor(s): Pandit; Nivedita (Middlebury, CT), Horhota; Stephen T. (Brookfield, CT)
Assignee: Boehringer Ingelheim Pharmaceuticals, Inc. (Ridgefield, CT)
Application Number:06/796,467
Patent Claim Types:
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Process; Formulation; Composition; Dosage form; Use;

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Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria31024► Subscribe
Australia2569684► Subscribe
Australia562929► Subscribe
Canada1212329► Subscribe
German Democratic Republic220225► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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