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Last Updated: December 19, 2025

Claims for Patent: 4,933,360

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Summary for Patent: 4,933,360

Title:	Novel chlorthalidone process and product
Abstract:	Water-soluble dispersions of chlorthalidone are prepared by a process comprising: (a) forming a solution comprising a water soluble pharmaceutically acceptable polymeric carrier and a C1-C4 alkanol, (b) dissolving chlorthalidone in the solution thus formed, and (c) removing the C1-C4 alkanol from the solution by evaporation, the amount of said carrier being effective to suppress substantially the formation of the alkyl ether by-product from the reaction of chlorthalidone with the C1-C4 alkanol. A preferred water soluble carrier is polyvinylpyrrolidone and a preferred C1-C4 alkanol is methanol.
Inventor(s):	Nivedita Pandit, Stephen T. Horhota
Assignee:	First Horizon Bank
Application Number:	US06/796,467
Patent Claims:

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