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Details for Patent: 4,920,143

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Summary for Patent: 4,920,143

Title: Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
Abstract:A group of hydro-monobenzoporphyrins "green porphyrins" (Gp) having absorption maxima in the range of 670-780 nanometers is useful in treating disorders or conditions which are subject to hematoporphyrin derivative (HPD) treatment in the presence of light, or in treating virus, cells and tissues generally to destroy unwanted targets. The use of the Gp of the invention permits the irradiation to use wavelengths other than those absorbed by blood. The Gp of the invention may also be conjugated to ligands specific for receptor or to specific immunoglobulins or fragments thereof to target specific tissues or cells for the radiation treatment. Use of these materials permits lower levels of drug to be used, thus preventing side reactions which might destroy normal tissues.
Inventor(s): Levy; Julia G. (Vancouver, CA), Dolphin; David (Vancouver, CA), Chow; Jack K. (Burnaby, CA), Sternberg; Ethan (Vancouver, CA)
Assignee: University of British Columbia (Vancouver, CA)
Application Number:07/221,161
Patent Claim Types:
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Compound; Composition;

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International Patent Family for Patent: 4,920,143

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria104859► subscribe
Austria127696► subscribe
Austria209650► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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