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|Abstract:||There are provided new cephem compounds (synisomers) represented by the following general formula (I): ##STR1## wherein R.sup.1 means a lower group, R.sup.2 denotes an ester-forming group of the carboxyl group, and the 4-methylthiazolyl group and the cephem moiety are cis to each other relative to the carbon-carbon double bond of the substituted vinyl group in the side chain at the 3-position of the cephem nucleus. The cephem compounds exhibit strong antibacterial activities not only against resistant strains of bacteria and gram-negative bacteria but also against gram-positive bacteria and moreover have very low toxicity.|
|Inventor(s):||Yamamoto; Yuichi (Yokohama, JP), Atsumi; Kunio (Kawasaki, JP), Sakagami; Kenji (Kawasaki, JP), Yoshida; Takashi (Tokyo, JP), Nishihata; Ken (Yokohama, JP), Kondo; Sinichi (Yokohama, JP)|
|Assignee:||Meiji Seika Kaisha, Ltd. (Tokyo, JP)|
Patent Claim Types:|
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|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Japan||61-44203||Mar 03, 1986|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|European Patent Office||0236231||► subscribe|
| This preview shows a limited data set|
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