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Details for Patent: 4,913,906

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Summary for Patent: 4,913,906

Title: Novel controlled release dosage form of valproic acid
Abstract:The invention relates to controlled release pharmaceutical compositions. These contain as active ingredient valproic acid, a salt of valproic acid, an ester of valproic acid, Valpromide, or any other pharmaceutically acceptable derivative of valproic acid which upon administration to humans provides a serum level of valproic acid, in combination with an additive which is selected from physiologically acceptable polymeric substances and from native proteins. The active ingredient is usually in the range of from 10 to 80 weight percent. The novel pharmaceutical compositions are prepared by applying a high pressure to a mixture of the ingredients. They result in a prolonged serum level of the active ingredient.
Inventor(s): Friedman; Michael (Jerusalem, IL), Bialer; Meir (Jerusalem, IL), Rubinstein; Avraham (Jerusalem, IL), Dufrovsky; Upd (Tel-Aviv, IL)
Assignee:
Application Number:06/832,244
Patent Claim Types:
see list of patent claims
Compound; Dosage form; Process;

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Foreign Priority and PCT Information for Patent: 4,913,906

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Israel74468Feb 28, 1985

International Patent Family for Patent: 4,913,906

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada2009890► subscribe
European Patent Office0442012► subscribe
Israel74468► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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