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Serving hundreds of leading biopharmaceutical companies globally:

Julphar
Teva
Cantor Fitzgerald
US Department of Justice
Baxter
Cipla
Chubb
Express Scripts
AstraZeneca

Generated: May 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,721,619

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Summary for Patent: 4,721,619
Title: Controlled absorption diltiazen pharmaceutical formulation
Abstract:A controlled absorption diltiazem formulation for oral administration comprises a pellet having a core of diltiazem or a pharmaceutically acceptable salt thereof in association with an organic acid and a lubricant, and an outer membrane which permits release of diltiazem in an aqueous medium at a controlled rate which is substantially pH independent. The pellet has a dissolution rate in vitro, which when measured according to the Paddle Method of U.S. Pharmacopoeia XX, is not more than 10% of the total diltiazem after 2 hours of measurement in a buffered medium. Not more than 30% of the total diltiazem is released after a total of 4 hours measurement and not more than 40% of the total diltiazem is released after a total of 6 hours. 100% release is achieved after 12 hours, with a maximum of 80% of the total diltiazem being released after 8 hours.
Inventor(s): Panoz; Donald E. (Whale Bay, BM), Geoghegan; Edward J. (Athlone, IE)
Assignee: Elan Corporation p.l.c. (IE)
Application Number:06/684,661
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 4,721,619
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound; Dosage form;

Drugs Protected by US Patent 4,721,619

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,721,619

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Ireland3057/83Dec 22, 1983

International Family Members for US Patent 4,721,619

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0149920 ➤ Try a Free Trial
European Patent Office 0320097 ➤ Try a Free Trial
European Patent Office 0856313 ➤ Try a Free Trial
Spain 2194832 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

QuintilesIMS
Express Scripts
Argus Health
Farmers Insurance
Colorcon
Cantor Fitzgerald
Deloitte
UBS
Fish and Richardson

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