Details for Patent: 4,636,505
✉ Email this page to a colleague
Summary for Patent: 4,636,505
Title: | Amide derivatives |
Abstract: | Acylanilides of the formula ##STR1## wherein R.sup.1 and R.sup.2, the same or different, each is cyano, carbamoyl, nitro, halogeno, perfluoroalkyl or other defined substituents; R.sup.3 is hydrogen or halogen; R.sup.4 is hydrogen or alkyl, or is joined to R.sup.5 ; R.sup.5 is hydrogen, hydroxy, alkoxy or acyloxy or is joined to R.sup.4 ; R.sup.6 is alkyl or halogenoalkyl, or has the formula --A.sup.3 --R.sup.8 or --A.sup.4 --X.sup.2 --A.sup.5 --R.sup.9 ; A.sup.1 and A.sup.4, the same or different, each is alkylene; A.sup.2, A.sup.3 and A.sup.5, the same or different, each is a direct link or alkylene; X.sup.1 and X.sup.2, the same or different, each is oxygen, sulphur, sulphinyl, sulphonyl, imino or alkylimino; R.sup.7 and R.sup.9, the same or different, each is alkyl, alkenyl, hydroxyalkyl, cycloalkyl, phenyl optionally substituted, naphthyl or heterocyclic optionally substituted; and R.sup.8 is phenyl, naphthyl or heterocyclic as defined above for R.sup.7 or R.sup.9 ; processes for their manufacture and pharmaceutical compositions containing them. The acylanilides possess antiandrogenic activity. |
Inventor(s): | Tucker; Howard (Macclesfield, GB) |
Assignee: | Imperial Chemical Industries PLC (London, GB2) |
Application Number: | 06/514,332 |
Patent Claim Types: see list of patent claims | Compound; Composition; Formulation; Dosage form; Use; |
Drugs Protected by US Patent 4,636,505
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 4,636,505
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
United Kingdom | 8221421 | Jul 23, 1982 |
International Family Members for US Patent 4,636,505
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Austria | 28864 | ⤷ Try a Trial | |||
Australia | 1693783 | ⤷ Try a Trial | |||
Australia | 556328 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |