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Generated: December 13, 2017

DrugPatentWatch Database Preview

Details for Patent: 4,636,505

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Summary for Patent: 4,636,505

Title: Amide derivatives
Abstract:Acylanilides of the formula ##STR1## wherein R.sup.1 and R.sup.2, the same or different, each is cyano, carbamoyl, nitro, halogeno, perfluoroalkyl or other defined substituents; R.sup.3 is hydrogen or halogen; R.sup.4 is hydrogen or alkyl, or is joined to R.sup.5 ; R.sup.5 is hydrogen, hydroxy, alkoxy or acyloxy or is joined to R.sup.4 ; R.sup.6 is alkyl or halogenoalkyl, or has the formula --A.sup.3 --R.sup.8 or --A.sup.4 --X.sup.2 --A.sup.5 --R.sup.9 ; A.sup.1 and A.sup.4, the same or different, each is alkylene; A.sup.2, A.sup.3 and A.sup.5, the same or different, each is a direct link or alkylene; X.sup.1 and X.sup.2, the same or different, each is oxygen, sulphur, sulphinyl, sulphonyl, imino or alkylimino; R.sup.7 and R.sup.9, the same or different, each is alkyl, alkenyl, hydroxyalkyl, cycloalkyl, phenyl optionally substituted, naphthyl or heterocyclic optionally substituted; and R.sup.8 is phenyl, naphthyl or heterocyclic as defined above for R.sup.7 or R.sup.9 ; processes for their manufacture and pharmaceutical compositions containing them. The acylanilides possess antiandrogenic activity.
Inventor(s): Tucker; Howard (Macclesfield, GB)
Assignee: Imperial Chemical Industries PLC (London, GB2)
Application Number:06/514,332
Patent Claim Types:
see list of patent claims
Compound; Composition; Formulation; Dosage form; Use;

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Foreign Priority and PCT Information for Patent: 4,636,505

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8221421Jul 23, 1982

International Patent Family for Patent: 4,636,505

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria28864► Subscribe
Australia1693783► Subscribe
Australia556328► Subscribe
Canada1249823► Subscribe
Czechoslovakia9103999► Subscribe
Germany3372965► Subscribe
Denmark322783► Subscribe
European Patent Office0100172► SubscribeSPC/GB95/015United Kingdom► Subscribe
European Patent Office0100172► Subscribe97C0010Belgium► Subscribe
Spain524392► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Cantor Fitzgerald
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