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Serving leading biopharmaceutical companies globally:

Chinese Patent Office
Daiichi Sankyo
Johnson and Johnson

Generated: October 23, 2017

DrugPatentWatch Database Preview

Details for Patent: 4,615,876

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Summary for Patent: 4,615,876

Title: Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
Abstract:Stable neutral-lipophilic complexes of technetium-99m (Tc-99m) useful as diagnostic radionuclidic imaging agents are formed by complexing technetium-99m pertechnetate with alkylene amine oximes (viz. propylene amine oxime) in aqueous solutions under reducing conditions. The complexes have a zero charge, contain an O--H--O ring closure bond, and are sufficiently stable for parental administration in imaging by scintillation scanning. Substituents can be attached to the C.sub.2 to C.sub.4 alkylene carbon backbone of the tetradentate amine oxime ligands to structurally modify them and produce a variety of Tc-99m-radiopharmaceuticals with specific body imaging applications.
Inventor(s): Troutner; David E. (Columbia, MO), Volkert; Wynn A. (Columbia, MO)
Assignee: Curators of the University of Missouri (Columbia, MO)
Application Number:06/488,184
Patent Claim Types:
see list of patent claims
Formulation; Dosage form;

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International Patent Family for Patent: 4,615,876

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia2711884► Subscribe
Australia564636► Subscribe
Canada1231715► Subscribe
Czechoslovakia271306► Subscribe
Czechoslovakia8403030► Subscribe
Germany123504► Subscribe
Germany3479801► Subscribe
Denmark173948► Subscribe
Denmark205284► Subscribe
European Patent Office0123504► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Federal Trade Commission
Cantor Fitzgerald
Fish and Richardson
Johnson and Johnson

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