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Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo
Fuji
Merck
Accenture
Citi
Colorcon
Moodys
Healthtrust
Argus Health

Generated: May 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,603,146

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Summary for Patent: 4,603,146
Title: Methods for retarding the effects of aging of the skin
Abstract:Various effects of aging of skin due to impairment of differentiation of epidermal epithelial cells and loss of collagen fibers, abnormal changes in elastic fibers and deterioration of small blood vessels in the dermis of the skin are retarded by applying topically to the epidermis in a maintenance therapy program effective amounts of vitamin A acid (tretinoin) such that epithelial growths are substantially reduced and prevented and the skin substantially regains and maintains its firmness, turgor and elasticity. Moreover, with persistent treatment dermal blood cells and vessels increase and the epidermis and dermis thicken, resulting in improved ability of the skin to sense, resist and recover from irritation or injury. Further, hyperpigmentation, lines and wrinkles due to aging are reduced and prevented. The treatment is particularly useful for human facial skin and preferably applied in amounts insufficient to cause excessive irritation.
Inventor(s): Kligman; Albert M. (Philadelphia, PA)
Assignee:
Application Number:06/759,505
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 4,603,146

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Family Members for US Patent 4,603,146

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0182183 ➤ Sign Up
European Patent Office 0230498 ➤ Sign Up
European Patent Office 0253393 ➤ Sign Up
Germany 3562543 ➤ Sign Up
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

AstraZeneca
Accenture
QuintilesIMS
Colorcon
Healthtrust
Fish and Richardson
Farmers Insurance
Covington
Harvard Business School

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