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|Title:||Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma|
|Abstract:||Ocular hypertension and glaucoma can be effectively controlled in primates through topical application of an effective amount of an eicosanoid or an eicosanoid derivative to the surface of an afflicted eye. Eicosanoids, particularly the prostaglandins PGE.sub.2 and PGF.sub.2.alpha., and derivatives thereof, have been found effective in quantities less than about 1000 .mu.g per eye. Ophthalmic compositions containing C.sub.1 to C.sub.5 alkyl esters of PGF.sub.2.alpha. are presently preferred for use in treating ocular hypertension and glaucoma in primates, including man.|
|Inventor(s):||Bito; Laszlo Z. (New York, NY)|
|Assignee:||The Trustees of Columbia University in the City of New York (New York, NY)|
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|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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