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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Colorcon
Daiichi Sankyo
Accenture
Fuji
Fish and Richardson
Cantor Fitzgerald
Baxter
Julphar

Generated: May 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,442,101

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Summary for Patent: 4,442,101
Title: Sesquihydrate of naphthyridine derivative, and process for the preparation thereof
Abstract:Novel 1-ethyl-6-fluoro-1,4-dihyono-4-oxo -7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid.sesquihydrate (ATT-2266.sesquihydrate). The aforesaid compound can be prepared by heating 1-ethyl-6-fluoro-1,4-dihydro-4-oxo -7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid at a temperature above about 60.degree. C. in the presence of water in an amount sufficient to form the sesquihydrate. This sesquihydrate is much more stable than the anhydrate and the trihydrate and is superior to the anhydrate in the rate of dissolution and transference into the body through the intestines. Thus, it is especially useful as a pharmaceutical compound.
Inventor(s): Ichihashi; Hitoshi (Kyoto, JP), Tanaka; Terukazu (Osaka, JP), Imasato; Yu (Toyonaka, JP)
Assignee: Dainippon Pharmaceutical Co., Ltd. (Osaka, JP) Laboratoire Roger Bellon (Neuilly sur Seine, FR)
Application Number:06/345,916
Patent Claim Types:
see list of patent claims
Compound; Use; Process; Composition;

Drugs Protected by US Patent 4,442,101

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,442,101

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan56-20749Feb 13, 1981

International Family Members for US Patent 4,442,101

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 8017382 ➤ Try a Free Trial
Australia 547082 ➤ Try a Free Trial
Canada 1216292 ➤ Try a Free Trial
Czechoslovakia 8200998 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Dow
Mallinckrodt
Moodys
Harvard Business School
Johnson and Johnson
Covington
Fish and Richardson
Cipla
Julphar

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