Details for Patent: 4,312,860

Summary for Patent: 4,312,860

Title:	Lung surfactant compositions
Abstract:	A synthetic protein-free lung surfactant composition is utilized to temporarily substitute for natural lung surfactant in the mammalian lung where such natural lung surfactant is absent or in low concentration. The synthetic surfactant composition consists essentially of a major amount of 1,2-dipalmitoyl-sn-3-glycerophosphoryl choline (DPPC), and a minor amount of a fatty alcohol, preferably a fatty alcohol having from 14 to 18 carbon atoms, and especially n-hexdecan-1-ol. The synthetic surfactant composition is administered directly into the lungs of a distressed subject to create a film on the alveolar interfacial surfaces and reduce surface tension. Expansion of the alveolar spaces is thereby facilitated.
Inventor(s):	John A. Clements
Assignee:	University of California , University of California San Diego UCSD
Application Number:	US06/200,216
Patent Claim Types: see list of patent claims	Use; Composition; Formulation;

Drugs Protected by US Patent 4,312,860

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

International Family Members for US Patent 4,312,860

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	0050793		94C0009	Belgium
European Patent Office	0050793		SPC/GB93/042	United Kingdom
Austria	7853
Bulgaria	60737
Canada	1184503
Czechoslovakia	9103849