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Details for Patent: 4,179,337

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Summary for Patent: 4,179,337

Title: Non-immunogenic polypeptides
Abstract:Polypeptides such as enzymes and insulin are coupled to polyethylene glycol or polypropropylene glycol having a molecular weight of 500 to 20,000 daltons to provide a physiologically active non-immunogenic water soluble polypeptide composition. The polyethylene glycol or polypropylene glycol protect the polypeptide from loss of activity and the composition can be injected into the mammalian circulatory system with substantially no immunogenic response.
Inventor(s): Davis; Frank F. (East Brunswick, NJ), Van Es; Theodorus (Piscataway, NJ), Palczuk; Nicholas C. (Bound Brook, NJ)
Application Number:05/819,831
Patent Claim Types:
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Composition; Compound; Process;

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International Patent Family for Patent: 4,179,337

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada1033673► subscribe
Switzerland616942► subscribe
Germany2433883► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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