Details for Patent: 4,179,337
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Summary for Patent: 4,179,337
Title: | Non-immunogenic polypeptides |
Abstract: | Polypeptides such as enzymes and insulin are coupled to polyethylene glycol or polypropropylene glycol having a molecular weight of 500 to 20,000 daltons to provide a physiologically active non-immunogenic water soluble polypeptide composition. The polyethylene glycol or polypropylene glycol protect the polypeptide from loss of activity and the composition can be injected into the mammalian circulatory system with substantially no immunogenic response. |
Inventor(s): | Davis; Frank F. (East Brunswick, NJ), Van Es; Theodorus (Piscataway, NJ), Palczuk; Nicholas C. (Bound Brook, NJ) |
Assignee: | |
Application Number: | 05/819,831 |
Patent Claim Types: see list of patent claims | Composition; Compound; Process; |
Drugs Protected by US Patent 4,179,337
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International Family Members for US Patent 4,179,337
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Canada | 1033673 | ⤷ Try a Trial | |||
Switzerland | 616942 | ⤷ Try a Trial | |||
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United Kingdom | 1469472 | ⤷ Try a Trial | |||
Israel | 45291 | ⤷ Try a Trial | |||
Japan | S5042087 | ⤷ Try a Trial | |||
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