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Details for Patent: 3,965,257

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Summary for Patent: 3,965,257

Title: Compositions and methods for the treatment of the symptoms of histamine induced allergic reactions
Abstract:Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##SPC1## Wherein R represents hydrogen or hydroxy; R.sup.1 represents hydrogen; or R and R.sup.1 taken together form a second bond between the carbon atoms bearing R and R.sup.1 ; n is a positive whole integer of from 1 to 3; Z represents thienyl, phenyl, or substituted phenyl wherein the substituents on the substituted phenyl may be attached at the ortho, meta, or para positions of the phenyl ring and are selected from halogen, a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, a lower alkoxy group of from 1 to 4 carbon atoms, di(lower)alkylamino, or a saturated monocyclic heterocyclic group such as pyrrolidino, piperidino, morpholino, or N-(lower)alkylpiperazino. Pharmaceutically acceptable acid addition salts and individual optical isomers of compounds of the above formula are also included as a part of this invention.
Inventor(s): Carr; Albert A. (Cincinnati, OH), Kinsolving; C. Richard (Cincinnati, OH)
Assignee: Richardson-Merrell Inc. (Wilton, CT)
Application Number:05/437,161
Patent Claim Types:
see list of patent claims
Composition; Compound; Dosage form; Use;

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International Patent Family for Patent: 3,965,257

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina195313► subscribe
Austria321912► subscribe
Austria321916► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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