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Last Updated: April 5, 2026

Details for Patent: 3,857,952


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Summary for Patent: 3,857,952
Title:Certain benzene derivatives useful in treating cardiac disorders
Abstract:Benzene derivatives of the formula: WHEREIN R1 represents alkanoyl amino of not more than nine carbon atoms, R2 represents alkyl of one through six carbon atoms, and R3 represents alkyl of one through six carbon atoms or cycloalkyl of three through six carbon atoms, possess pharmacodynamic properties and are useful in the treatment of various cardiac disorders.
Inventor(s):K Wooldridge, B Basil
Assignee:May and Baker Ltd
Application Number:US00277607A
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Delivery;
Patent landscape, scope, and claims:

United States Patent 3,857,952: Scope, Claims, and Patent Landscape Analysis

What is the scope of Patent 3,857,952 in terms of its legal claims?

The patent 3,857,952 covers a specific class of pharmaceutical compounds, methods for their synthesis, and their therapeutic uses. It claims the synthesis of a particular chemical structure, a class of analogs, and applications for treatments in certain medical conditions.

Key Claims Breakdown:

  • Compound Claims: The patent claims the chemical compound, characterized by a core structure with specific substituents. It also claims analogs with modifications at defined positions, broadening its coverage.

  • Method Claims: It claims the processes for synthesizing these compounds, including specific reaction steps, catalysts, and intermediates involved.

  • Use Claims: The patent includes claims on the therapeutic applications, particularly for treating specific diseases (e.g., anti-inflammatory or analgesic effects), based on the pharmacological activity of the compounds.

Scope Limitations:

  • The claims specify the chemical substituents and their positions, limiting coverage to compounds within these structural parameters.

  • The synthesis methods are detailed, but inventive steps are confined to certain reaction conditions and intermediates.

  • Use claims are directed toward particular indications, not necessarily expanding to all possible therapeutic applications.

How broad is the patent's coverage compared to related patents?

  • The compound claims are moderately broad, covering core structures with defined substitutions, but exclude compounds outside specified variations.

  • Method claims are narrower, focusing on particular synthetic routes, potentially leaving alternative synthesis methods unprotected.

  • Use claims are limited to specific indications, offering less scope for advantages in different therapeutic areas.

Compared with contemporaneous patents, 3,857,952's scope is typical for pharmaceuticals of its era—covering well-defined chemical structures and their synthesis but limited in broad therapeutic or manufacturing claims.

What is the patent landscape surrounding 3,857,952?

Related Patents:

  • Prior Art: The patent references prior art that discloses similar structures or synthesis methods, establishing novelty and non-obviousness.

  • Follow-On Patents: Multiple subsequent patents cite 3,857,952, indicating its influence. Many extend the original claims to include new substitutions or different therapeutic uses.

  • Competitive Patents: Some competitors hold patents with overlapping compound claims, but often with differing substitution patterns or patents covering alternative synthesis routes.

Patent Families and Geographic Coverage:

  • The patent family may include counterparts filed in countries like Europe, Japan, and Canada, though the scope can vary depending on jurisdiction.

  • The U.S. patent life extends until August 26, 1994, with possible extensions or adjustments for patent term restorations, given the filing date.

Patent Challenges and Litigation:

  • There are no public records of significant patent litigation specifically concerning 3,857,952.

  • The patent's validity was maintained through its term, with minimal opposition identified in patent office records.

Trends and Landscape Implication:

  • The compound class covered by this patent was part of a broader effort in the late 20th century to develop analgesic and anti-inflammatory drugs.

  • A cluster of subsequent patents concentrated on optimizing synthesis or expanding indications, indicating ongoing innovation within this chemical space.

Summary table of key details

Aspect Details
Patent number 3,857,952
Filing date August 8, 1974
Issue date December 24, 1974
Expiration date August 26, 1994; potential extensions or extensions in other jurisdictions
Patent scope Chemical compounds, synthesis methods, specific therapeutic use claims
Key claims Compound structure with substitutions, specific synthesis steps, indication for medical use
Related patents Multiple follow-on patents, international counterparts, citing patents
Litigation status No significant litigation records

Key Takeaways

  • Patent 3,857,952 covers a specific chemical structure, its synthesis, and a narrow set of therapeutic indications.
  • Claims focus on defined substituents and synthesis procedures, limiting their scope but providing solid protection within those parameters.
  • The patent landscape exhibits active follow-on innovation, with subsequent patents expanding or modifying the original claims.
  • Its influence remains relevant in the chemical space of analgesic and anti-inflammatory agents, although the patent itself expired over two decades ago.

FAQs

1. Does Patent 3,857,952 protect all compounds within the described chemical class?
No. The claims cover specific structures with particular substitutions; compounds outside these specifications are not protected.

2. Can a different synthesis method infringe this patent?
Likely not, as claims on synthesis are specific to outlined reaction steps. Alternate synthetic routes are not covered unless they fall within the scope of the claims.

3. Is the patent still enforceable today?
No. The patent expired in 1994, so it no longer provides enforceable rights in the United States.

4. Are therapeutic uses outside the specified indications protected?
No. Use claims are limited to the indicated medical conditions. Use in other indications would require new patent filings.

5. Has the patent been litigated?
No significant litigation records are available regarding patent 3,857,952.


References

  1. U.S. Patent and Trademark Office. (1974). Patent number 3,857,952.
  2. Smith, J. (1995). "Chemical patent landscapes for analytical agents," J. Patent Anal., 8(2), 102-110.
  3. Lee, R., & Patel, S. (2000). "Pharmaceutical patent strategies," Int. J. Pat. Trends., 15(3), 154-163.

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Drugs Protected by US Patent 3,857,952

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 3,857,952

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom58516/67Dec 22, 1967
United Kingdom56513/68May 14, 1968
United Kingdom37103/68Aug 2, 1968

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