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|Title:||NOVEL PEPTIDES HAVING CHOLECYSTOKININ ACTIVITY AND INTERMEDIATES THEREFOR|
|Abstract:||Novel peptide amides of the general formula R-Met-Gly-Trp-Met-Asp-Phe-NH.sub.2 wherein R represents L-aspartyl-O-sulfate-L-tyrosyl, L-aspartyl-L-arginyl-L-aspartyl-O-sulfate-L-tyrosyl, or isoleucyl-L-seryl-L-aspartyl-L-arginyl-L-aspartyl-O-sulfate-L-tyrosyl, and intermediates in the production thereof. The peptide amides of this invention as well as the pharmaceutically acceptable salts thereof have been found to possess cholecystokinin activity.|
|Inventor(s):||Ondetti; Miguel A. (North Brunswick, NJ), Pluscec; Josip (East Brunswick, NJ), Sheehan; John T. (Middlesex, NJ), Jorpes; Johan E. (Stockholm, SW), Mutt; Viktor (Farsta, SW)|
|Assignee:||E. R. Squibb & Sons, Inc. (New York, NY)|
Patent Claim Types:|
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|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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