Last Updated: June 18, 2026

Details for Patent: 12,377,133


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Which drugs does patent 12,377,133 protect, and when does it expire?

Patent 12,377,133 protects YUVIWEL and is included in one NDA.

This patent has twenty patent family members in twelve countries.

Summary for Patent: 12,377,133
Title:Dry pharmaceutical formulations of CNP conjugates
Abstract:A dry pharmaceutical formulation, wherein the pharmaceutical formulation comprises a CNP conjugate, a buffering agent and a bulking agent and wherein the CNP conjugate comprises a CNP moiety that is covalently and reversibly conjugated to a polymeric moiety.
Inventor(s):Anja R. H. Skands, Ulrich Hersel, Charlotte PINHOLT, Stefan HEINIG
Assignee: Ascendis Pharma Endocrinology Division AS
Application Number:US17/428,604
Patent Claim Types:
see list of patent claims
Use; Formulation;

Drugs Protected by US Patent 12,377,133

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Ascendis YUVIWEL navepegritide POWDER;SUBCUTANEOUS 219164-001 Feb 27, 2026 RX Yes Yes 12,377,133 ⤷  Start Trial Y INCREASE OF LINEAR GROWTH IN PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER WITH ACHONDROPLASIA WITH OPEN EPIPHYSES ⤷  Start Trial
Ascendis YUVIWEL navepegritide POWDER;SUBCUTANEOUS 219164-002 Feb 27, 2026 RX Yes Yes 12,377,133 ⤷  Start Trial Y INCREASE OF LINEAR GROWTH IN PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER WITH ACHONDROPLASIA WITH OPEN EPIPHYSES ⤷  Start Trial
Ascendis YUVIWEL navepegritide POWDER;SUBCUTANEOUS 219164-003 Feb 27, 2026 RX Yes Yes 12,377,133 ⤷  Start Trial Y INCREASE OF LINEAR GROWTH IN PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER WITH ACHONDROPLASIA WITH OPEN EPIPHYSES ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 12,377,133

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2020223441 ⤷  Start Trial
Australia 2025210778 ⤷  Start Trial
Brazil 112021014495 ⤷  Start Trial
Canada 3129352 ⤷  Start Trial
China 113423384 ⤷  Start Trial
China 117281783 ⤷  Start Trial
European Patent Office 3923906 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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