Last Updated: September 24, 2026

Details for Patent: 12,115,255

Name: Drug Patent Intelligence for US Patent 12115255
Creator: DrugPatentWatch
License: https://www.drugpatentwatch.com/terms.php

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Which drugs does patent 12,115,255 protect, and when does it expire?

Patent 12,115,255 protects APONVIE and CINVANTI and is included in two NDAs.

Summary for Patent: 12,115,255

Title:	Methods of use of emulsion formulations of an NK-1 receptor antagonist
Abstract:	Disclosed herein are novel pharmaceutical formulations of a neurokinin-1 (NK-1) receptor antagonist suitable for parenteral administration including intravenous administration. Also included are formulations including both the NK-1 receptor antagonist and dexamethasone sodium phosphate. The pharmaceutical formulations are stable oil-in-water emulsions for non-oral treatment of emesis and are particularly useful for treatment of subjects undergoing highly emetogenic cancer chemotherapy.
Inventor(s):	Thomas B. Ottoboni, Han Han
Assignee:	Heron Therapeutics LLC
Application Number:	US18/418,030
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 12,115,255
Patent Claim Types: see list of patent claims

Drugs Protected by US Patent 12,115,255

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Heron Theraps Inc	APONVIE	aprepitant	EMULSION;INTRAVENOUS	216457-001	Sep 16, 2022		RX	Yes	Yes	12,115,255	⤷ Start Trial	Y				⤷ Start Trial
Heron Theraps Inc	CINVANTI	aprepitant	EMULSION;INTRAVENOUS	209296-001	Nov 9, 2017		RX	Yes	Yes	12,115,255	⤷ Start Trial	Y				⤷ Start Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

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