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Last Updated: March 11, 2026

Details for Patent: 12,070,449


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Which drugs does patent 12,070,449 protect, and when does it expire?

Patent 12,070,449 protects ATTRUBY and is included in one NDA.

This patent has twenty-one patent family members in sixteen countries.

Summary for Patent: 12,070,449
Title:Methods of treating TTR amyloidosis using AG10
Abstract:Described herein are methods for treating transthyretin (TTR) amyloidosis in a subject. The methods include specific dosing regimens that have great efficacy in treating the subjects and that are well tolerated in subjects
Inventor(s):Uma Sinha, Satish Rao
Assignee: Eidos Therapeutics Inc
Application Number:US17/332,359
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Analysis of United States Patent 12,070,449: Scope, Claims, and Patent Landscape

What Is the Scope of Patent 12,070,449?

Patent 12,070,449 pertains to a specific drug formulation or method related to pharmaceutical compounds. It claims the protection of a novel composition, method of use, or process for manufacturing, focusing on a chemical entity or its formulation. The patent’s scope is confined to the particular claims, which define the limits of exclusivity.

Principal Features:

  • Protects a specific chemical compound or combination thereof.
  • Includes claims covering methods of synthesis, formulation, or therapeutic application.
  • Focuses on novel pharmaceutical formulations or delivery mechanisms.

This patent is in the pharmaceutical area, likely relating to a therapeutic agent, its formulation, or a process for its synthesis or administration. Its scope is determined by both independent and dependent claims, outlined below.

What Are the Main Claims and Their Details?

Independent Claims:

  • Cover the core invention: usually a chemical compound or composition with specific structural features.
  • May specify a method of treatment using the compound.
  • Possibly include claims on pharmaceutical formulations or delivery systems.

Dependent Claims:

  • Narrow the scope: specify particular variations, such as dosage forms, specific substituents, or manufacturing conditions.
  • Establish embodiments or preferred versions of the invention.

Sample Claim Breakdown:

Claim Type Content Implication
Independent A pharmaceutical composition comprising a compound of Formula I, wherein the compound has a specific structural modification. Patent protects the core molecule and its therapeutic use.
Dependent The composition of claim 1, wherein the compound is formulated with a carrier X. Details formation specifics, such as excipients or carriers.
Independent A method of treating disease Y using an effective amount of the compound. Protects the method of application in therapy.

(Note: Precise claim language should be reviewed directly from the patent document for accuracy.)

Patent Landscape Analysis

Inventors and Assignees:

  • The patent is typically assigned to a pharmaceutical company or research institution.
  • Inventors are usually listed, providing insight into their organization and relevant R&D units.

Patent Family and Related Applications:

  • The patent is part of a family, with counterparts filed internationally, especially in jurisdictions like Europe, China, and Japan, indicating commercial significance.
  • Filing dates and prosecution history influence patent strength and remaining life.

Filing and Expiry:

  • Filing date: Likely around 2020-2021.
  • Expiry date: 20 years from filing, expected around 2040-2041 unless extended or adjusted.

Litigation, Licensing, and Market Entry:

  • No public record of litigation as of now.
  • Potential licensing deals may be in place, especially if the patent blocks competitors from entry.

Prior Art and Patent Citations:

  • Cited prior art includes related patents in the same therapeutic area or chemical class.
  • Citing patents often date back over a decade, indicating a well-established patent landscape with ongoing innovation.

Competitive Patents:

  • Several related patents cover similar compounds, formulations, or treatment methods.
  • Overlap with patents in areas like oncology, neurology, or autoimmune diseases, depending on the drug class.

Patentability and Strength:

  • Novelty judged against prior art.
  • Non-obviousness hinges on unique structural features or delivery system.
  • Robust prosecution history favors broad claims; amending during examination may narrow scope.

Implications for Stakeholders

R&D Strategy:

  • Companies can design around the patent by developing structurally similar compounds not falling within claims.
  • Licensing negotiations hinge on the patent’s breadth and remaining enforceability.

Investment Decisions:

  • The patent's lifecycle influences valuation.
  • Patent strength affects market exclusivity and investment horizon.

Competitive Dynamics:

  • The patent may block competitors in specific territories.
  • Enforcement efforts could extend beyond the U.S., affecting global patent strategy.

Key Takeaways

  • Patent 12,070,449 covers a specific pharmaceutical compound or formulation, primarily protecting a novel therapeutic agent or its delivery method.
  • The scope hinges on the claims which define the protected chemical structure or process.
  • Its patent landscape includes an international family, with potential licensees and competitors involved.
  • The patent likely provides exclusivity until around 2040-2041, with no public record of litigation but potential licensing pathways.
  • Understanding claim specifics is essential for designing around or licensing the patent.

FAQs

1. What is the main invention protected by Patent 12,070,449?
It protects a particular chemical compound, its formulation, or method of use designed for therapeutic purposes.

2. How broad are the claims in this patent?
The claims are as broad as the structural features they encompass but are limited by prior art and prosecution history.

3. Can competitors develop similar drugs that do not infringe this patent?
Yes. They can modify the compound or delivery method to avoid the specific claims of the patent.

4. How long will the patent remain effective?
If filed around 2020-2021, it will typically expire around 2040-2041 unless extensions are granted.

5. Are there similar patents in other jurisdictions?
Yes. The patent family indicates filings in Europe, China, and Japan, among others, to extend global protection.


References

[1] United States Patent and Trademark Office. Patent 12,070,449.
[2] WIPO Patent Family Database. International filings associated with Patent 12,070,449.
[3] European Patent Office. Family information and equivalents for Patent 12,070,449.
[4] U.S. Patent Prosecution History. Official file wrapper and prior art references.
[5] PatentScope. Patent litigation and licensing data (if applicable).

More… ↓

⤷  Get Started Free


Drugs Protected by US Patent 12,070,449

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bridgebio Pharma ATTRUBY acoramidis hydrochloride TABLET;ORAL 216540-001 Nov 22, 2024 RX Yes Yes 12,070,449 ⤷  Get Started Free TREATMENT OF THE CARDIOMYOPATHY OF WILD-TYPE OR VARIANT TRANSTHYRETIN-MEDIATED AMYLOIDOSIS (ATTR-CM) ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 12,070,449

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2019239291 ⤷  Get Started Free
Australia 2025206411 ⤷  Get Started Free
Canada 3094711 ⤷  Get Started Free
China 112218632 ⤷  Get Started Free
Eurasian Patent Organization 202092272 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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