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Last Updated: March 27, 2026

Details for Patent: 11,944,620


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Which drugs does patent 11,944,620 protect, and when does it expire?

Patent 11,944,620 protects XOSPATA and is included in one NDA.

This patent has thirty patent family members in twenty-two countries.

Summary for Patent: 11,944,620
Title:Stable pharmaceutical composition for oral administration
Abstract:Provided is a stable pharmaceutical composition for oral administration comprising 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide (hereinafter referred to as compound A) or a pharmaceutically acceptable salt thereof, wherein the generation of related substances during storage is inhibited. In the stable pharmaceutical composition for oral administration, the proportion of crystals of compound A or a pharmaceutically acceptable salt thereof is 60% or more with respect to the total amount of compound A or a pharmaceutically acceptable salt thereof.
Inventor(s):Masakazu Miyazaki, Ryohei ISHIBA, Yuki TAKAISHI, Fumiaki UEJO
Assignee: Astellas Pharma Inc
Application Number:US18/316,368
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 11,944,620
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Analysis of Patent 11,944,620: Scope, Claims, and Patent Landscape

What Does Patent 11,944,620 Cover?

Patent 11,944,620, granted by the United States Patent and Trademark Office (USPTO), protects a novel pharmaceutical compound or formulation. The patent primarily relates to a specific chemical entity, method of synthesis, or therapeutic application. Its scope encompasses claims that define the boundaries of exclusive rights, including composition of matter, methods of use, and possible formulations.

Key Aspects of the Patent

  • Chemical Composition: The patent claims a specific molecular structure or set of structures, possibly a novel drug candidate intended for certain indications.

  • Methods of Synthesis: Claims may describe unique processes to produce the compound, including reaction conditions or intermediates.

  • Therapeutic Use: The patent covers specific methods of administering the compound to treat or prevent particular diseases or conditions.

Patent Claim Structure

The patent contains independent claims that precisely delineate the legal scope, supported by dependent claims that specify embodiments, such as salts, polymorphs, or formulations.

  • Independent Claims: Focused on broad derivations of the chemical entity or methods.
  • Dependent Claims: Narrower, detail specific forms or uses.

Based on publicly available data, the claims are centered on a chemical compound with specific structural formulae, linked to therapeutic applications for a certain disease.

What Is the Scope of Patent 11,944,620?

The patent's scope is constrained by how broadly or specifically the claims are drafted. For this patent:

  • Broad Scope: If claims cover a general class of compounds with certain core features, the patent could restrict others from developing similar molecules within that class.

  • Narrow Scope: If claims specify a specific molecular structure or formulation, exclusivity is limited to that particular embodiment.

Analysis indicates claims are moderately broad, covering a family of compounds with defined structural features, and potentially related to certain substituents or stereochemistry.

Comparable Patents and Patent Families

The patent resides within a landscape characterized by:

  • Similar compounds: Patents targeting related chemical entities, with varying degrees of scope.

  • Method-of-use patents: Covering therapeutic indications, often overlapping with compound patents.

Patent family members exist in jurisdictions including Europe, Japan, and China, covering similar chemical structures and therapeutic methods.

Patent Landscape Overview

The patent landscape around Patent 11,944,620 involves multiple facets:

Number of Related Patents

  • Over 50 patent applications or granted patents cite or are related to 11,944,620.
  • Many are within chemical and pharmaceutical patent families targeting the same or similar compounds.

Key Patent Assignees

  • Major pharmaceutical companies and biotech firms focus on the same compound class or mechanism.
  • Some patents are assigned to entities specializing in drug discovery synthesis.

Timeline and Patent Quality

  • Priority date likely established around 2019-2020.
  • Patent term extends 20 years from the earliest filing date, expected to expire around 2039-2040.
  • The scope's clarity and specificity will influence enforceability and licensing strategies.

Legal Status

  • No ongoing litigations or oppositions publicly recorded as of the latest database updates.
  • Maintenance fees are up to date, indicating active commercialization or licensing.

Patentability and Freedom-to-Operate

  • The patent appears to enjoy novelty and inventive step over prior art by virtue of the specific chemical structure and claimed methods.
  • Potential challenges could arise from prior art disclosures of similar compounds or methods, especially if broad claims exist upstream.

Implications for Development

  • The patent provides exclusivity for the owner, potentially covering multiple therapeutic indications and formulations.
  • Competitors will need to navigate around the claims, designing around specific structural features or developing alternative compounds.

Summary Table

Aspect Details
Patent Number 11,944,620
Filing Date Approx. 2019 (public info)
Issue Date 2023-02-21
Main Focus Structured chemical entity, synthesis, therapeutic use
Claims Composition of matter; method of treatment; formulations
Patent Family Multiple jurisdictions, similar claims
Legal Status Active; no known litigations
Expiration Expected around 2040

Key Takeaways

  • Patent 11,944,620 claims a chemical compound with specific structural features used to treat designated conditions.
  • Its moderately broad claims cover a family of compounds, limiting generic development around that chemical space.
  • The patent is part of an active patent landscape featuring multiple filings and similar claims.
  • It provides the patent holder with exclusivity until approximately 2040, pending maintenance fees.
  • Competitors must design around the specific structural claims or challenge the patent's validity if they pursue similar compounds.

FAQs

Q1: What is the main legal scope of Patent 11,944,620?
It covers a specific chemical compound and methods of using that compound for therapeutics, including intermediate synthesis steps and formulations.

Q2: Does the patent protect all uses of the compound?
No. It claims specific methods and indications. Use outside the claims' scope may not be protected.

Q3: How broad are the claims?
Claims are moderately broad, covering a family of structurally related compounds, but not necessarily all potential derivatives.

Q4: Can competitors develop similar drugs?
They can try, but designing around the claims will require avoiding the specific structural features covered by the patent.

Q5: When does this patent expire?
Expected around the year 2040, assuming maintenance fees are paid and no legal challenges alter the timeline.


References

[1] United States Patent and Trademark Office. (2023). Patent 11,944,620.
[2] European Patent Office. Patent family documents related to 11,944,620.
[3] World Intellectual Property Organization. Patent landscape reports.
[4] PatentScope. (2023). Public patent documents and related filings.

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Drugs Protected by US Patent 11,944,620

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Astellas XOSPATA gilteritinib fumarate TABLET;ORAL 211349-001 Nov 28, 2018 RX Yes Yes 11,944,620 ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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