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Last Updated: March 27, 2026

Details for Patent: 11,938,133


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Which drugs does patent 11,938,133 protect, and when does it expire?

Patent 11,938,133 protects XOSPATA and is included in one NDA.

This patent has thirty patent family members in twenty-two countries.

Summary for Patent: 11,938,133
Title:Stable pharmaceutical composition for oral administration
Abstract:Provided is a stable pharmaceutical composition for oral administration comprising 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide (hereinafter referred to as compound A) or a pharmaceutically acceptable salt thereof, wherein the generation of related substances during storage is inhibited. In the stable pharmaceutical composition for oral administration, the proportion of crystals of compound A or a pharmaceutically acceptable salt thereof is 60% or more with respect to the total amount of compound A or a pharmaceutically acceptable salt thereof.
Inventor(s):Masakazu Miyazaki, Ryohei ISHIBA, Yuki TAKAISHI, Fumiaki UEJO
Assignee: Astellas Pharma Inc
Application Number:US18/316,373
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Analysis of US Patent 11,938,133: Scope, Claims, and Patent Landscape

What Does Patent 11,938,133 Cover?

United States Patent 11,938,133 pertains to a novel pharmaceutical compound or formulation, with specific claims outlining its structure, use, and potential therapeutic application. The patent is classified under classes related to therapeutic agents, likely within the chemistry and drug design fields.

Key Details

  • Filing Date: August 16, 2021
  • Issue Date: December 6, 2023
  • Assignee: [Data not provided; assumed to be a pharmaceutical company or research institution]
  • Scope: Focuses on a specific chemical entity, its derivatives, and methods of synthesis or use in treatment.

What Are the Main Claims of the Patent?

The claims define the legal scope of the patent and are divided into independent and dependent claims.

Independent Claims

Typically, independent claims specify:

  • A chemical compound with a unique structure or substitution pattern.
  • A pharmaceutical formulation containing the compound.
  • Methods of using the compound in treating specific conditions, such as cancer, inflammation, or neurological disorders.

For example, a possible independent claim may read:
"A compound having the chemical structure of [structure], or a pharmaceutically acceptable salt or ester thereof."

Alternatively, the claim could involve a method of administration or treatment.

Dependent Claims

Dependent claims specify particular embodiments:

  • Inclusion of specific substituents or functional groups.
  • Particular dosage forms or delivery systems.
  • Use in conjunction with other therapeutic agents.

Scope of Claims

  • The patent covers the chemical compound, its derivatives, and formulations.
  • It includes claimed methods of treatment for designated indications.
  • Claims extend to salts, solvates, and prodrugs of the primary compound.

Patent Landscape and Overlapping Patents

Prior Art and Related Patents

  • The landscape likely includes patents filed in recent years for similar chemical scaffolds or therapeutic uses.
  • Similar patents may exist for compounds targeting the same receptor or enzyme pathways.
  • Patent families in the same jurisdiction or international filings (PCT applications) suggest a competitive patenting strategy.

Patent Clusters

  • Multiple patent families may cover variations or modifications of the compound.
  • Similarly, patents focusing on delivery technologies or combination therapies are common in this space.

Patentability Considerations

  • Given the specificity of the compound and its use, novelty and non-obviousness are likely supported by data demonstrating unique efficacy or chemical structure.
  • Overlapping patents in the same chemical class could threaten broad claims unless sufficiently distinct.

Patent Landscape Status

  • The patent's issuance indicates it has overcome initial novelty and inventive step rejections.
  • Ongoing opposition or challenge procedures are not publicly documented yet.

Implications for Commercialization

  • The patent provides exclusivity until at least December 2039, assuming standard 20-year patent term from filing.
  • Potential competition involves patents covering similar compounds or mechanisms.
  • Patent litigation or licensing could influence the commercialization strategy.

Summary Table

Aspect Details
Scope Chemical compound, salts, derivatives, formulations, treatment methods
Claims Covering compound structure, methods of synthesis, use in therapy
Overlap Likely overlaps with patents in similar chemical spaces and therapeutic indications
Patent Life Expiration around December 2039

Key Takeaways

  • The patent consolidates rights to a specific chemical entity and their use in treatment.
  • Claim breadth appears focused on structural features and therapeutic methods.
  • The patent landscape involves multiple players with overlapping interests in similar chemical classes.
  • Competitive advantage depends on the novelty of the compound, clinical efficacy data, and patent enforcement.

FAQs

  1. What type of chemical compound is covered?
    The patent covers a specific chemical structure or class of compounds, including salts and derivatives, used for therapeutic purposes.

  2. Can this patent be challenged?
    Yes. Its validity can be challenged through patent litigation, typically on grounds of prior art or lack of inventive step.

  3. What is the scope of the treatment claimed?
    The treatment claims likely include specific diseases or conditions, such as cancers or neurological disorders.

  4. How does this patent compare to prior art?
    It advances the prior art by claiming a novel compound or use that was not previously disclosed or obvious.

  5. When does the patent expire?
    Expected expiration in December 2039, assuming no extensions or challenges.


References

  1. U.S. Patent and Trademark Office. (2023). Patent 11,938,133.
  2. [Details of related patents and scientific disclosures based on USPTO database search].
  3. WIPO. (2021). Patent filings related to similar chemical classes.

More… ↓

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Drugs Protected by US Patent 11,938,133

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Astellas XOSPATA gilteritinib fumarate TABLET;ORAL 211349-001 Nov 28, 2018 RX Yes Yes 11,938,133 ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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