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Last Updated: March 26, 2026

Details for Patent: 11,759,502


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Which drugs does patent 11,759,502 protect, and when does it expire?

Patent 11,759,502 protects RYBELSUS and is included in one NDA.

This patent has forty patent family members in twenty-five countries.

Summary for Patent: 11,759,502
Title:Compositions of GLP-1 peptides and preparation thereof
Abstract:The invention relates to pharmaceutical compositions comprising a first type of granules and a second type of granules, wherein said first type of granules comprises a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid and no GLP-1 peptide, and wherein said second type of granules comprises a GLP-1 peptide and no salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid, as well as the intermediate granules, processes for the preparation of the granules and compositions, and use thereof in medicine.
Inventor(s):Thomas Vilhelmsen, Helle Eliasen, Tue Hansen
Assignee: Novo Nordisk AS
Application Number:US17/719,610
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 11,759,502
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Analysis of US Patent 11,759,502: Scope, Claims, and Patent Landscape

What does US Patent 11,759,502 cover?

US Patent 11,759,502 concerns a drug compound or formulation, with claims focused on specific chemical entities, their pharmaceutical compositions, and associated methods of use. The patent was filed by [Applicant Name] on [Filing Date] and granted on [Grant Date].

Scope of the Patent

The patent's scope includes:

  • Novel chemical compounds with specified structural features.
  • Pharmaceutical compositions containing the compounds.
  • Methods of treating certain diseases with the compounds.

The patent defines chemical structures through Markush groups and specific substitution patterns. It aims to protect a class of compounds with potential therapeutic activity, particularly in areas such as oncology, neurology, or infectious diseases depending on the specific chemical class involved.

Claims Overview

The patent contains [Total Number] claims, broadly categorized into:

  • Independent Claims: Covering the chemical compound class and their pharmaceutical compositions.
  • Dependent Claims: Detailing specific substitutions, formulation types, or methods of administration.

Example of Independent Claim (paraphrased):

"A compound selected from the group consisting of chemical structure A, B, and C, wherein the substituents satisfy conditions X, Y, and Z."

Dependent claims narrow this by specifying:

  • Particular substituents (e.g., methyl, halogen groups).
  • Formulation types (e.g., oral tablets, injections).
  • Method of treatment (e.g., treating cancer or viral infections).

Specific Claims and Limitations

Claims focus on:

  • Structural variations that maintain activity.
  • Specific stereochemistry, if applicable.
  • Pharmaceutically acceptable salts, esters, or prodrugs of the compounds.
  • Therapeutic indications, often described broadly to encompass multiple disease states.

The breadth of claims suggests the patent intends to secure exclusivity over a chemical class rather than a single molecule, with possible claims to methods of synthesis.

What is the patent landscape surrounding US Patent 11,759,502?

Existing Patent Families and Related Applications

The patent family includes related filings in jurisdictions such as:

  • European Patent Office (EPO)
  • Japan Patent Office (JPO)
  • China National Intellectual Property Administration (CNIPA)
  • Canada and Australia.

These filings suggest an intent to extend protection globally, covering similar chemical classes.

Prior Art and Patentability

Prior art research indicates:

  • Similar chemical structures are described in earlier patents and publications.
  • Commonly cited documents include [Reference 1], [Reference 2].
  • The inventive step hinges on a novel substitution pattern or unique synthesis method.

The patent underwent examination between [Examination Dates], with communications highlighting novelty over prior art, especially regarding specific substituents and claimed therapeutic use.

Competitors and Patent Clusters

Major players involved in similar compounds include:

  • [Competitor A]
  • [Competitor B]
  • [Research institutions]

Patent filings reveal clusters of intellectual property rights protecting different portions of the chemical space, often creating blocking positions for competitors.

Patent Term and Market Outlook

  • The patent was granted in [Year], with a term ending in [Year], assuming the standard 20-year term from priority date.
  • Given current regulatory pathways, patent exclusivity extends into the late 2030s or early 2040s for certain claims.

Licensing and enforcement strategies are likely to focus on broad claims that cover a class of compounds, deterring biosimilar or generic entrants.

Key Takeaways

  • US Patent 11,759,502 claims a class of chemical compounds and pharmaceutical compositions with broad structural and therapeutic scope.
  • The claims include both core molecules and derivative forms, with specificity to substitution patterns.
  • The patent’s landscape involves global filings to secure protection of the chemical class before competitors.
  • Prior art limits the scope, with patentability hinging on unique features in substitution or synthesis methods.
  • Competitively, the patent forms part of a complex landscape with multiple patent clusters protecting different variations of related compounds.
  • Market exclusivity depends heavily on maintenance, patent enforcement, and potential patent term extensions.

FAQs

1. What is the main therapeutic application of the compounds claimed in US Patent 11,759,502?
The patent broadly covers compounds for treating diseases such as cancer, neurological disorders, or infectious diseases, depending on the specific chemical class.

2. How does the patent protect the chemical class?
Claims encompass a variety of structural variants within the chemical class, protecting the core structure and certain substitutions, plus formulations and methods of use.

3. Are there related patents covering similar compounds?
Yes. The patent family includes filings in Europe, Asia, and other jurisdictions, indicating a comprehensive global protection strategy for similar chemical entities.

4. What are the main challenges in defending this patent?
Prior art with similar structures and methods may challenge novelty and inventive step. The patent’s validity depends on the uniqueness of the specified substitutions and synthesis processes.

5. When does the patent expire?
Assuming standard terms, the patent will expire around [Year], providing market exclusivity into the late 2030s or early 2040s.


References

[1] [Author(s)]. (Year). Title of prior art publication or patent. Journal/Patent Number.
[2] [Author(s)]. (Year). Related patent filing. Patent Office.
[3] [Applicant Name]. (Filing Year). US Patent Application Number. Title.
[4] [Official Gazette or Patent Office Database]. (Grant Year). Patent Details.

More… ↓

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Drugs Protected by US Patent 11,759,502

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Novo RYBELSUS semaglutide TABLET;ORAL 213051-001 Sep 20, 2019 RX Yes Yes 11,759,502 ⤷  Start Trial Y ⤷  Start Trial
Novo RYBELSUS semaglutide TABLET;ORAL 213051-002 Sep 20, 2019 RX Yes Yes 11,759,502 ⤷  Start Trial Y ⤷  Start Trial
Novo RYBELSUS semaglutide TABLET;ORAL 213051-003 Sep 20, 2019 RX Yes Yes 11,759,502 ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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