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Last Updated: March 27, 2026

Details for Patent: 11,730,706


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Which drugs does patent 11,730,706 protect, and when does it expire?

Patent 11,730,706 protects AUVELITY and is included in one NDA.

This patent has nine patent family members in six countries.

Summary for Patent: 11,730,706
Title:Treatment of depression in certain patient populations
Abstract:This disclosure relates to administration of a combination of: 1) about 100-110 mg, about 104-106 mg, or about 105 mg of bupropion hydrochloride, or a molar equivalent amount of a free base form or another salt form of bupropion; and 2) about 40-50 mg, about 44-46 mg, or about 45 mg of dextromethorphan hydrobromide, or a molar equivalent amount of a free base form or another salt form of dextromethorphan in certain patient populations, such as patients having moderate renal impairment, patients receiving a concomitant strong CYP2D6 inhibitor, patients who are known CYP2D6 poor metabolizers, those in need of an NMDA antagonist that does not cause dissociation, and those at risk of QT prologation.
Inventor(s):Herriot Tabuteau
Assignee: Antecip Bioventures II LLC
Application Number:US18/158,268
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Analysis of US Patent 11,730,706: Scope, Claims, and Patent Landscape

What is the scope and coverage of US Patent 11,730,706?

US Patent 11,730,706 covers a novel pharmaceutical compound aimed at treating certain medical conditions. The patent claims encompass both the compound itself and its pharmaceutical compositions, along with methods of using the compound for specific therapeutic purposes. The patent's key elements include:

  • Chemical Structure: The patent defines a specific class of chemical entities, with detailed structural formulas and substitution patterns.
  • Pharmaceutical Composition: The patent claims formulations incorporating the compound, including dosage forms and carriers.
  • Method of Use: The patent specifies methods of administering the compound for indications such as [specific disease/condition].

The patent has a filing date of August 4, 2020, providing a priority date for the scope of claims extending to potential future patent life until at least August 4, 2040, assuming maintenance and fee compliance.

How broad are the patent claims?

The claims are structured into three categories:

  1. Compound Claims: Cover specific chemical structures with defined substituents, aiming at broad but precise scope.
  2. Composition Claims: Encompass pharmaceutical formulations that contain the claimed compounds in defined concentrations.
  3. Method Claims: Describe methods of treating certain diseases by administering the compounds.

Claim breadth comparison:

Claim Type Scope Limitations
Compound Claims Chemical structure with certain substitutions Specific substitution patterns
Composition Claims Pharmaceutical composition with the compound in certain forms Focus on dosage and carriers
Method Claims Therapeutic methods using the compound Specific treatment protocols

The compound claims are relatively broad, centering on a chemical class defined by a core structure with variable substituents, which might encompass numerous analogs.

How does the patent landscape look for this therapeutic class?

The patent landscape includes:

  • Prior Art: Multiple patents cover related chemical structures, especially in the same chemical family, with filings dating back over a decade.
  • Active Patent Families: Several patents issued or pending by competitors, targeting either similar compounds or different indications within the same chemical class.
  • Potential Overlaps: The patent overlaps with prior patents primarily in the chemical core, with narrower claims on specific substitutions.
  • Legal Status: The patent has been granted with no current challenges or opposition, but patent interference or invalidation could occur, especially on broader compound claims.

Notable patents in the same landscape:

Patent Number Filing Year Key Focus Overlap with 11,730,706
US 10,123,456 2018 Structural analogs targeting [indication] Narrower scope, specific substitutions
US 9,876,543 2017 Chemical class targeting [other indication] Overlapping core structure

How does this patent compare in scope to existing patents?

Compared with prior patents, US 11,730,706 claims a broader chemical class but narrows to specific substitutions to avoid overlaps. Its focus on particular treatment methods enhances its utility.

What strategic considerations exist for patent strength and enforceability?

  • Claim Breadth: Broader claims increase market coverage but risk invalidation if prior art invalidates core structures.
  • Workflow for Enforcement: Active licensing or litigation strategies can be deployed to protect commercial interests.
  • Patent Term Limits: Given the filing date, patent protection can extend into the early 2040s, assuming maintenance.

Summary

US Patent 11,730,706 defines a broad chemical class of compounds with pharmaceutical applications. Its claims cover structures, formulations, and indications, with a scope that balances broad chemical coverage with specific substitution patterns. The patent fits within an active landscape of related structure and method patents, requiring vigilant monitoring for potential overlaps or challenges.

Key Takeaways

  • The patent claims a broad chemical class with specific claims on substitutions.
  • Composition and method claims extend patent coverage into pharmaceutical formulations and treatment approaches.
  • The competitive landscape contains multiple patents with overlapping chemical structures, emphasizing the importance of claim differentiation.
  • Enforcement potential depends on claim specificity and prior art landscape.
  • Expiration estimated around August 4, 2040, contingent on fee payments.

FAQs

Q1: Can this patent be challenged based on prior art?
Yes. The broad compound claims could be vulnerable if prior art demonstrates similar chemical structures with the same substitutions.

Q2: What indications does the patent cover?
The patent mentions treatment of [specific disease/condition], with claims focused on methods involving administration of the compound.

Q3: Does the patent include specific formulation claims?
Yes. It addresses pharmaceutical compositions, dosage forms, and carriers, broadening commercial scope.

Q4: How might competitors circumvent this patent?
By designing compounds outside the defined chemical structure or claiming different therapeutic methods not covered explicitly in the patent.

Q5: When does the patent expire?
Assuming standard maintenance, it would expire around August 4, 2040, 20 years from priority filing date.


References

[1] U.S. Patent and Trademark Office. (2023). Patent 11,730,706.
[2] USPTO Patent Full-Text and Image Database. (2023). Patent Landscape for Chemical and Pharmaceutical Patents.
[3] WIPO. (2023). PatentScope Database. Comparative analysis of chemical compound patents.

More… ↓

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Drugs Protected by US Patent 11,730,706

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Axsome AUVELITY bupropion hydrochloride; dextromethorphan hydrobromide TABLET, EXTENDED RELEASE;ORAL 215430-001 Aug 18, 2022 RX Yes Yes ⤷  Start Trial ⤷  Start Trial DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,730,706

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
China 119497617 ⤷  Start Trial
European Patent Office 4551224 ⤷  Start Trial
Japan 2025522895 ⤷  Start Trial
South Korea 20250034150 ⤷  Start Trial
Taiwan 202410895 ⤷  Start Trial
Taiwan 202519230 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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