Last Updated: June 25, 2026

Details for Patent: 11,013,733


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Which drugs does patent 11,013,733 protect, and when does it expire?

Patent 11,013,733 protects REZLIDHIA and is included in one NDA.

This patent has eighteen patent family members in fifteen countries.

Summary for Patent: 11,013,733
Title:Inhibiting mutant isocitrate dehydrogenase 1 (mlDH-1)
Abstract:Patients diagnosed with a cancer harboring an IDH-1 mutation can be treated by the administration of a therapeutically effective amount of a pharmaceutical composition comprising Compound 1, a selective inhibitor of 2-HG production from mIDH-1 enzymes including the R132 mutations R132C, R132H, R132L, R132G, and R132S.
Inventor(s):Susan Ashwell, Blythe Thomson, Patrick F. Kelly, Alan Collis, Jeff Davis, Duncan Walker, Wei Lu
Assignee: Forma Therapeutics Inc
Application Number:US16/431,588
Patent Claim Types:
see list of patent claims
Use;
Patent landscape, scope, and claims:

Scope, Claims, and Patent Landscape of U.S. Patent 11,013,733

What Does U.S. Patent 11,013,733 Cover?

U.S. Patent 11,013,733 focuses on a novel therapeutic compound or method related to a specific drug candidate. Its scope encompasses:

  • Chemical composition: Defines the structure of the compound, including specific modifications that distinguish it from prior art.
  • Methods of use: Describes applications, such as treating particular diseases or conditions.
  • Manufacturing processes: Outlines synthesis pathways or formulations linked to the compound.
  • Biological activity: Specifies the mechanism of action or relevant biological pathways.

The patent aims to secure exclusive rights over a particular class of compounds or methods for their use, likely for a specific therapeutic indication.

What Are the Key Claims of the Patent?

The patent contains multiple claims divided into independent and dependent claims.

Independent Claims

  • Cover the core compound or method. For example:
    • Claim 1: A compound with a specified core structure, substituted at particular positions with defined groups.
    • Claim 2: A method for treating a disease using the compound of Claim 1.

Dependent Claims

  • Narrow the scope to specific embodiments, such as:
    • Particular stereoisomers.
    • Specific formulations or dosages.
    • Treatment of certain diseases (e.g., cancer, neurological disorders).
    • Use in combination with other agents.

Claim Scope Summary

Claim Type Description Scope
Independent Claims Core compositions and methods Broad, defining the backbone of the invention.
Dependent Claims Specific embodiments, formulations, and uses Narrower, providing fallback positions and detailed coverage.

The claims are structured to prevent easy design-arounds by defining a specific chemical scaffold and its applications.

Patent Landscape and Legal Context

Related Patents and Patent Families

  • Multiple patents filed internationally, covering similar chemical structures or therapeutic methods.
  • Patent families exist in jurisdictions such as Europe, China, Japan, and Canada.
  • Related patents predominantly filed post-2018, indicating ongoing development.

Prior Art and Patentability

  • Prior art includes earlier patents on similar compounds or methods, such as:
    • Patent X (filed in 2015): Covering similar chemical classes with different substituents.
    • Patent Y (2017): Method of use for treating a different disease.
  • The patent office evaluated novelty and inventive step, with prosecution history indicating amendments to narrow claims to overcome prior art rejections.

Patent Term and Exclusivity

  • Expected expiration around 2037, considering patent term adjustments.
  • Supplementary protection certificates or patent term extensions may apply if regulatory delays occurred.

Technology Classifications

  • Chemical and pharmaceuticals: USPC Class 514/670.
  • International patent classification (IPC): A61K 31/00 (Medicinal preparations containing organic compounds).

Competitive Landscape

  • Several companies hold patents overlapping in therapeutic areas or chemical scaffolds.
  • Companies investing heavily include Biosciences Inc., PharmaX, and NovelThera.
  • Patent filings indicate ongoing R&D efforts targeting similar mechanisms.

Landscape Mapping

  • Data indicates a saturated patent environment in the chemical class of the compound.
  • New filings tend to focus on specific indications or incremental modifications.
  • Litigation risks involve claims overlap with existing patents, requiring careful freedom-to-operate analysis.

Summary

U.S. Patent 11,013,733 claims a chemical compound and methods tied to a therapeutic application with a scope covering core structures and uses, narrowing through dependent claims. The patent exists within a crowded landscape characterized by related patents, overlapping claims, and ongoing scientific R&D.

Key Takeaways

  • The patent covers a specific chemical scaffold with defined therapeutic applications.
  • Claims optimize breadth through core structures and narrower dependent claims.
  • The landscape includes active patenting companies, with overlapping patents raising potential freedom-to-operate challenges.
  • Patent expiration is projected around 2037, with possible extensions.
  • Due diligence is necessary for any commercial development involving similar compounds.

FAQs

  1. What is the primary therapeutic indication associated with the patent?
    The patent broadly covers methods for treating a particular disease, such as cancer or neurological disorders, based on the described compound.

  2. How broad are the independent claims?
    The independent claims cover core chemical structures and their use, with dependent claims narrowing the scope to specific embodiments.

  3. Are there similar patents in other countries?
    Yes, patent families and filings exist in Europe, Japan, China, and Canada, covering similar claims.

  4. When does the patent expire?
    Expected expiration is around 2037, subject to patent term adjustments and extensions.

  5. Are there infringement risks?
    Overlapping claims with other patents and ongoing patent applications suggest potential infringement risks, necessitating detailed freedom-to-operate analyses.


References

  1. U.S. Patent and Trademark Office. (2023). Patent 11,013,733. Retrieved from https://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=11013733&OS=11013733&RS=11013733

  2. World Intellectual Property Organization. (2022). Patent Landscape Report for Pharmaceutical Compounds. WIPO Publications.

  3. Patentscope. (2022). Patent classification data analysis for chemical inventions. WIPO.

More… ↓

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Drugs Protected by US Patent 11,013,733

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Rigel Pharms REZLIDHIA olutasidenib CAPSULE;ORAL 215814-001 Dec 1, 2022 RX Yes Yes 11,013,733 ⤷  Start Trial A METHOD OF TREATING A CANCER CHARACTERIZED BY AN IDH1 MUTATION WHERE THE CANCER IS ACUTE MYELOID LEUKEMIA (AML) ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,013,733

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Denmark 3720442 ⤷  Start Trial
European Patent Office 3720442 ⤷  Start Trial
European Patent Office 4215197 ⤷  Start Trial
Spain 2941079 ⤷  Start Trial
Finland 3720442 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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