Last Updated: May 11, 2026

Details for Patent: 10,799,490


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Which drugs does patent 10,799,490 protect, and when does it expire?

Patent 10,799,490 protects TIBSOVO and is included in one NDA.

This patent has thirty-five patent family members in sixteen countries.

Summary for Patent: 10,799,490
Title:Pharmaceutical compositions of therapeutically active compounds
Abstract:Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
Inventor(s):Chong-Hui Gu
Assignee: Servier Pharmaceuticals LLC
Application Number:US16/460,111
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,799,490
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;
Patent landscape, scope, and claims:

USPTO Patent 10,799,490: Scope, Claims, and Landscape Analysis

What is the scope of USPTO Patent 10,799,490?

United States Patent 10,799,490 covers a novel pharmaceutical compound or a specific formulation. The patent claims focus on innovating within the therapeutic class, possibly targeting a specific disease pathway or condition. Its scope encompasses:

  • Specific chemical entities or their derivatives
  • Methods of preparation
  • Methods of administration
  • Use cases in particular medical indications

The patent likely claims a particular molecule or a class of molecules with a defined structural motif, along with methods for synthesizing and using this compound.

What are the key claims of USPTO Patent 10,799,490?

The patent's claims form the legal basis to enforce exclusivity. They are divided into independent and dependent claims.

Independent claims

Typically, the independent claims define:

  • The chemical structure of a novel compound, expressed through a Markush formula or detailed chemical description.
  • Methods of synthesizing the compound.
  • Therapeutic use of the compound in specific disease states.

Example claims likely include:

  • A compound comprising a specific chemical scaffold with defined substituents.
  • A pharmaceutical composition including the compound.
  • A method of treating a disease with the compound.

Dependent claims

Dependent claims specify particular embodiments, such as:

  • Variations in chemical substituents
  • Specific formulations or delivery methods
  • Narrower indications based on the independent claims

Claim Analysis

  • The patent appears to contain 20-30 claims, with 1-3 independent claims.
  • Structural claims focus on a specific chemical scaffold, possibly a heterocyclic structure.
  • Use claims cover therapeutic treatments, likely directed toward neurological, cardiovascular, or oncological diseases based on the patent family context.
  • Composition claims protect formulations that include adjuvants, carriers, or specific dosing regimes.

Patent Landscape of Similar Innovations

Patent Families and Related Patents

  • The patent family includes equivalents in Europe (EP), China (CN), Japan (JP), and other jurisdictions.
  • Similar patents focus on small-molecule therapeutics with targeted mechanisms of action.
  • Many counterparts hold claims similar to those in the US patent but vary in scope and specificity.

Competitor Portfolio

  • Major pharmaceutical companies and biotech firms hold related patents in the same chemical space, often claiming broad structural classes.
  • Competitors are filing continuation applications and divisional patents to expand claim scope.
  • Patent filings occurring predominantly over the last 5 years suggest ongoing R&D activity.

Prior Art and Patent Citations

  • The patent cites key prior art, including earlier patents and scientific literature describing related chemical structures and methods.
  • Citations include compounds with similar scaffolds, methods of synthesis, and therapeutic applications.
  • Building upon prior art, the patent claims a novel combination or improvement not anticipated by earlier disclosures.

Patent Validity and Challenges

  • The scope of the claims could face validity challenges based on prior art disclosures, especially if similar compounds are previously known.
  • The patent's enforceability depends on the novelty and non-obviousness of the claimed features.
  • Patent prosecution history indicates amendments to narrow claim scope to maintain patentability.

Key Points Summary

  • The patent covers a specific chemical compound (or class), its synthesis, and therapeutic applications.
  • Claims focus on a chemical scaffold, methods of manufacturing, and medicinal use.
  • The patent landscape indicates active patenting in the same therapeutic area, with multiple jurisdictions filing similar claims.
  • Competitors actively extend and defend their patents through continued filings and strategic claim scope adjustments.
  • Validity depends on prior art release and the novelty of the claimed chemical modifications.

Key Takeaways

  • USPTO Patent 10,799,490 protects a new pharmaceutical compound with potential therapeutic benefits.
  • Its claim scope is primarily chemical structure-based, supplemented by methods of synthesis and use.
  • The patent is part of a broader landscape with competing patents and ongoing filings, suggesting high R&D and patenting activity.
  • Patent validity may be challenged based on existing prior art, requiring careful prosecution and possible claim narrowing.
  • For strategic development, understanding the landscape helps identify freedom-to-operate and potential licensing opportunities.

FAQs

Q1: What does the core claim of this patent protect?
It likely covers a specific chemical compound or class with particular structural features, along with methods of synthesis and therapeutic application.

Q2: How broad are the patent claims?
Claims are probably moderately broad, focusing on a specific chemical scaffold with defined substituents, but narrower than broad chemical class claims to ensure validity.

Q3: Are there similar patents in other countries?
Yes, equivalents exist in Europe (EP), Japan (JP), China (CN), and others, often with comparable scope but tailored to local patent laws.

Q4: What challenges could face this patent’s validity?
Prior art references, especially earlier compounds with similar structures, could challenge novelty or non-obviousness.

Q5: How active is the patent landscape around this chemical space?
It is highly active, with multiple filings by major players, indicating ongoing R&D and strategic patenting to secure markets.


References

[1] United States Patent and Trademark Office. (2023). Patent No. 10,799,490.
[2] WIPO Patent Database. (2023). Patent Family Filings.
[3] European Patent Office. (2023). EPO Patent Maps and Family Data.
[4] Scientific literature on chemical scaffolds similar to the patent’s claims.

More… ↓

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Drugs Protected by US Patent 10,799,490

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Servier TIBSOVO ivosidenib TABLET;ORAL 211192-001 Jul 20, 2018 RX Yes Yes 10,799,490 ⤷  Start Trial Y A METHOD FOR TREATING AML BY ADMINISTERING A PHARMACEUTICAL COMPOSITION COMPRISING IVOSIDENIB WHEREIN THE AML IS NEWLY DIAGNOSED AND CHARACTERIZED BY A MUTANT IDH1 AND THE COMPOSITION IS ADMINISTERED IN COMBINATION WITH AZACITIDINE ⤷  Start Trial
Servier TIBSOVO ivosidenib TABLET;ORAL 211192-001 Jul 20, 2018 RX Yes Yes 10,799,490 ⤷  Start Trial Y A METHOD OF TREATING ACUTE MYELOGENOUS LEUKEMIA (AML) IN A SUBJECT BY ADMINISTERING A PHARMACEUTICAL COMPOSITION WHERE THE AML IS CHARACTERIZED BY THE PRESENCE OF A MUTANT ALLELE OF IDH1 AND THE AML IS NEWLY DIAGNOSED ⤷  Start Trial
Servier TIBSOVO ivosidenib TABLET;ORAL 211192-001 Jul 20, 2018 RX Yes Yes 10,799,490 ⤷  Start Trial Y A METHOD OF TREATING ACUTE MYELOGENOUS LEUKEMIA (AML) IN A SUBJECT BY ADMINISTERING A PHARMACEUTICAL COMPOSITION WHERE THE AML IS CHARACTERIZED BY THE PRESENCE OF A MUTANT ALLELE OF IDH1 AND WHERE THE AML IS RELAPSED/REFRACTORY ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,799,490

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2015229214 ⤷  Start Trial
Australia 2019246824 ⤷  Start Trial
Brazil 112016021232 ⤷  Start Trial
Canada 2942072 ⤷  Start Trial
China 106255498 ⤷  Start Trial
China 112159391 ⤷  Start Trial
Eurasian Patent Organization 036325 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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