Last Updated: May 6, 2026

Details for Patent: 10,563,259


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Which drugs does patent 10,563,259 protect, and when does it expire?

Patent 10,563,259 protects BYSANTI and is included in one NDA.

This patent has sixteen patent family members in seven countries.

Summary for Patent: 10,563,259
Title:Method of treatment based on polymorphisms of the KCNQ1 gene
Abstract:The invention provides methods for the administration of compounds capable of prolonging a QTc interval and methods for predicting whether an individual is predisposed to such QTc prolongation.
Inventor(s):Curt D. Wolfgang, Mihael H. Polymeropoulos
Assignee: Vanda Pharmaceuticals Inc
Application Number:US15/705,048
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 10,563,259

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Vanda Pharms Inc BYSANTI milsaperidone TABLET;ORAL 220358-001 Feb 20, 2026 RX Yes Yes 10,563,259 ⤷  Start Trial METHOD FOR ACUTE TREATMENT OF MANIC OR MIXED EPISODES ASSOCIATED WITH BIPOLAR I DISORDER IN ADULTS BY ADMINISTERING MILSAPERIDONE TO A PATIENT BY LOWERING THE DOSE AFTER DETERMINING THAT THE PATIENT HAS A GENETIC PREDISPOSITION FOR QT PROLONGATION ⤷  Start Trial
Vanda Pharms Inc BYSANTI milsaperidone TABLET;ORAL 220358-001 Feb 20, 2026 RX Yes Yes 10,563,259 ⤷  Start Trial METHOD FOR TREATMENT OF SCHIZOPHRENIA IN ADULTS BY ADMINISTERING MILSAPERIDONE TO A PATIENT BY LOWERING THE DOSE AFTER DETERMINING THAT THE PATIENT HAS A GENETIC PREDISPOSITION FOR QT PROLONGATION ⤷  Start Trial
Vanda Pharms Inc BYSANTI milsaperidone TABLET;ORAL 220358-002 Feb 20, 2026 RX Yes No 10,563,259 ⤷  Start Trial METHOD FOR ACUTE TREATMENT OF MANIC OR MIXED EPISODES ASSOCIATED WITH BIPOLAR I DISORDER IN ADULTS BY ADMINISTERING MILSAPERIDONE TO A PATIENT BY LOWERING THE DOSE AFTER DETERMINING THAT THE PATIENT HAS A GENETIC PREDISPOSITION FOR QT PROLONGATION ⤷  Start Trial
Vanda Pharms Inc BYSANTI milsaperidone TABLET;ORAL 220358-002 Feb 20, 2026 RX Yes No 10,563,259 ⤷  Start Trial METHOD FOR TREATMENT OF SCHIZOPHRENIA IN ADULTS BY ADMINISTERING MILSAPERIDONE TO A PATIENT BY LOWERING THE DOSE AFTER DETERMINING THAT THE PATIENT HAS A GENETIC PREDISPOSITION FOR QT PROLONGATION ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,563,259

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada 2757713 ⤷  Start Trial
European Patent Office 2417267 ⤷  Start Trial
European Patent Office 3023506 ⤷  Start Trial
European Patent Office 3354753 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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