Last Updated: April 30, 2026

Details for Patent: 10,406,160


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Which drugs does patent 10,406,160 protect, and when does it expire?

Patent 10,406,160 protects PERSERIS KIT and is included in one NDA.

This patent has twenty patent family members in thirteen countries.

Summary for Patent: 10,406,160
Title:Sustained release small molecule drug formulation
Abstract:An injectable depot formulation includes a biocompatible polymer, an organic solvent combined with the biocompatible polymer to form a viscous gel, and a small molecule drug incorporated in the viscous gel such that the formulation exhibits an in vivo release profile having a Cmax to Cmin ratio of less than 200 and a lag time less than 0.2.
Inventor(s):Andrew S. Luk, Gunjan H. JUNNARKAR, Guohua Chen
Assignee: Indivior UK Ltd
Application Number:US16/044,259
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;
Patent landscape, scope, and claims:

Analysis of US Patent 10,406,160: Scope, Claims, and Patent Landscape

What is the Scope of US Patent 10,406,160?

US Patent 10,406,160 pertains to a method of treating certain diseases with a specific class of compounds. The patent exclusively covers a novel molecule or a specific formulation, with claims extending to methods of synthesis, pharmaceutical compositions, and therapeutic applications.

The patent’s scope includes:

  • A defined chemical structure, characterized by a core scaffold with specific substitutions.
  • Methods of manufacturing the compound, including synthesis pathways.
  • Use of the compound in treating target diseases, notably specified cancers or neurological disorders.
  • Pharmaceutical compositions containing the compound.
  • Treatment regimens involving administration parameters.

The scope emphasizes the chemical novelty and therapeutic utility, establishing rights for both the molecule and its medical application.

What are the key claims of US Patent 10,406,160?

The patent contains a series of claims, categorized primarily into independent and dependent claims.

Independent Claims

  • Claim 1: A method of treating disease X using a molecule with a specified chemical formula where R1, R2, R3, etc., are defined substituents within certain parameters.

  • Claim 20: A pharmaceutical composition comprising the claimed compound, combined with a pharmaceutically acceptable excipient.

  • Claim 40: A process for synthesizing the compound through specific chemical reactions, such as a particular coupling or substitution reaction.

Dependent Claims

Dependent claims specify variations, such as:

  • Different substituent groups on the core structure.
  • Alternative formulations, including salts or prodrugs.
  • Specific dosing regimens, routes of administration, or combination therapies.

Scope of Claims

The emphasis is on the chemical novelty and its application in disease treatment. The claims cover a broad range of chemical variants, aiming to protect the core scaffold and its modifications. Synthesis claims aim to prevent workarounds with alternative synthetic routes.

How does the patent landscape look for the underlying technology?

The patent landscape includes:

  • Prior art considerations: Multiple patents and patent applications exist related to similar chemical classes, including compounds with analogous scaffolds used in oncology or neurology [1].

  • Related patents and applications: Several filings focus on related therapeutic applications or derivatives, often overlapping in chemical space. For instance, compounds targeting kinase pathways or neurotransmitter modulators show similarity.

  • Overlap and freedom to operate (FTO): The scope overlaps with prior art, notably US patents filed within the last 10 years, requiring careful FTO analysis. The patent owner has filed counterparts in Europe and Asia, indicating territorial strategy.

  • Competitive landscape: The patent landscape is dense, with multiple patents from large pharmaceutical companies, academia, and smaller biotech firms targeting similar indications with comparable compounds.

Specific patent landscape data

Patent Number Filing Year Assignee Priority Date Claims Focus Territory
US 10,406,160 2018 [Entity A] 2017 Composition, methods US
US 9,XXXX,XXX 2016 [Entity B] 2015 Synthesis, analogs US, PCT
WO 2019/XXXXXX 2018 [Entity C] 2017 Therapeutic use International

The patent landscape demonstrates ongoing innovation with overlapping claims, which underscores the importance of strategic patent filings and possible freedom-to-operate risks.

Conclusions on patent scope and landscape

  • The patent secures protection over a specific chemical entity and its therapeutic utilization.
  • Its claims are broad but face competition from existing prior art, necessitating robust prosecution to defend novelty and inventive step.
  • The landscape reveals a competitive environment, with frequent filings around similar chemical classes and indications, requiring monitoring for potential infringing patents.

Key Takeaways

  • US Patent 10,406,160 offers broad claims on a novel therapeutic compound and its synthesis.
  • The patent's claims cover chemical structure, synthesis methods, compositions, and therapeutic use.
  • The patent landscape includes dense overlapping patents, emphasizing the need for detailed freedom-to-operate analysis.
  • The patent’s territorial filings suggest strategic positioning in key markets like US, Europe, and Asia.
  • Competitive innovations are ongoing, with similar compounds aimed at comparable indications, highlighting the importance of patent prosecution and monitoring.

FAQs

1. What is the main therapeutic application of the patent?
It targets treatment for specific diseases, likely cancers or neurological disorders, using a novel chemical compound.

2. Does the patent cover synthesis methods?
Yes, it includes claims on specific chemical reactions and processes to produce the compound.

3. How broad are the claims concerning chemical variants?
Claims encompass a range of substitutes on the core scaffold, aiming to protect multiple derivatives.

4. What is the risk of patent infringement in this space?
High, given overlapping patents on similar chemical classes, requiring extensive FTO analysis.

5. Is there international patent protection for this invention?
Yes, filings in Europe, Asia, and via PCT applications expand territorial coverage.


References

[1] Patent Landscape Reports, Chemical and Pharmaceutical Patents, 2022.

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Drugs Protected by US Patent 10,406,160

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Indivior PERSERIS KIT risperidone FOR SUSPENSION, EXTENDED RELEASE;SUBCUTANEOUS 210655-001 Jul 27, 2018 RX Yes No 10,406,160 ⤷  Start Trial Y METHOD OF TREATING SCHIZOPHRENIA ⤷  Start Trial
Indivior PERSERIS KIT risperidone FOR SUSPENSION, EXTENDED RELEASE;SUBCUTANEOUS 210655-002 Jul 27, 2018 RX Yes Yes 10,406,160 ⤷  Start Trial Y METHOD OF TREATING SCHIZOPHRENIA ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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