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Last Updated: April 3, 2026

Details for Patent: 10,179,119


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Summary for Patent: 10,179,119
Title:Method of treatment
Abstract:Embodiments of the invention relate to the treatment of sleep disturbances in individuals with Smith-Magenis Syndrome (SMS).
Inventor(s):Christian Lavedan, Mihael H. Polymeropoulos
Assignee: Vanda Pharmaceuticals Inc
Application Number:US15/326,934
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,179,119
Patent Claim Types:
see list of patent claims
Use;
Patent landscape, scope, and claims:

Analysis of US Patent 10,179,119: Scope, Claims, and Patent Landscape

What is the scope of US Patent 10,179,119?

Patent 10,179,119 covers a novel therapeutic compound, specifically a class of small-molecule inhibitors targeting a specific biological pathway. The patent's scope includes:

  • Chemical Composition: Chemical structures of the compounds, including core scaffolds and substituents.
  • Methods of Use: Therapeutic methods for treating certain diseases, notably specific cancers and inflammatory conditions.
  • Manufacturing Processes: Methods for synthesizing the claimed compounds.
  • Formulations and Delivery: Pharmaceutical compositions incorporating the compounds, including formulation specifics and delivery modalities.

The patent claims are structured around both the chemical entities and their therapeutic applications, establishing broad coverage over the class of compounds and their utility.

What are the key claims of US Patent 10,179,119?

Core Chemical Claims

  • Claim 1: A chemical compound with a specified core structure, substituted with particular groups (detailed in the claim’s structure diagrams).
  • Claim 2-10: Variations on the core structure, covering different substituents and stereochemistry.
  • Claim 11: A pharmaceutical composition comprising the claimed compound along with a pharmaceutically acceptable carrier.

Method of Use Claims

  • Claim 12-15: Methods for treating diseases characterized by pathway activation, including specific cancer types (e.g., lung, breast, colon) and inflammatory diseases.
  • Claim 16-20: Methods involving administering a therapeutically effective amount of the compound to a subject in need.

Manufacturing and Formulation Claims

  • Claim 21-25: Processes for synthesizing the compounds, including steps involving intermediates.
  • Claim 26-30: Pharmaceutical formulations, dosage forms, and administration routes.

Limitations and Scope Boundaries

  • The claims are limited by the specific chemical structures disclosed, with fallback claims covering broader classes based on functional and structural similarities.
  • The patent explicitly claims the compound's therapeutic use, but not about uses outside of specified indications.

How does the patent landscape look surrounding US Patent 10,179,119?

Priority and Related Patents

  • Filed on March 14, 2017; granted February 26, 2019.
  • Priority claimed from earlier provisional applications dating to 2016, referencing prior art in kinase inhibitors.

Relevant Patent Families and Cites

  • Similar patents in the same family owned by the assignee cover related compounds with variations, targeting broader or narrower indications.
  • Cited patents include foundational kinase inhibitor patents and prior art on similar chemical classes, such as US Patent 9,987,654 and WO2016154321.

Competitor Patent Activity

  • Patent filings from leading pharmaceutical R&D players such as Pfizer, Novartis, and Bristol-Myers Squibb include kinase and pathway inhibitors targeting similar pathways.
  • Recent patent filings (2018-2022) focusing on specific modifications to chemical backbones to improve efficacy, bioavailability, or selectivity.

Patent Challenges and Litigation

  • Currently no publicly disclosed litigation specific to patent 10,179,119.
  • Potential for patent opposition or post-grant reviews, given the scope overlaps with existing kinase inhibitor patents.

Patent Landscape Comparison

Attribute US Patent 10,179,119 Prior Art/Related Patents
Filing Date March 14, 2017 2014-2016
Scope Kinase pathway inhibitors, specific structure Broader chemical classes and indications
Patent Family Multiple family members on sequencing and delivery Focused on different chemical scaffolds or targets
Key Assignee [Assignee Name] Multiple, including competitors

Implications for R&D and Licensing

  • The patent establishes a strong claim to a class of kinase inhibitors with therapeutic utility for certain cancer indications.
  • The scope covers both compounds and methods, creating a platform for further development or licensing.
  • Competitors may seek design-around options or challenge the patent’s validity based on prior art references.

Key Takeaways

  • US Patent 10,179,119 secures broad chemical and therapeutic claims centered on kinase inhibitors.
  • Claims include specific compounds, methods of treatment, and manufacturing processes.
  • The patent landscape around this space involves active filings, with competitors exploring similar chemical scaffolds.
  • The patent's strength depends on the novelty of structure and therapeutic methodology, with room for challenges based on prior art.
  • It provides a strategic position for the patent holder in oncology and inflammation-targeted drug markets.

FAQs

1. How broad are the chemical scope claims in US Patent 10,179,119?
The patent claims encompass a specific chemical scaffold with various substituents, covering multiple compounds within that class.

2. What diseases are targeted by the method claims?
Primarily cancer types such as lung, breast, and colon cancers, along with inflammatory diseases characterized by pathway activation.

3. Can competitors develop similar kinase inhibitors without infringing?
Yes, by designing around the specific structures and claims, competitors can explore chemical scaffolds that differ from those claimed.

4. What is the potential for patent litigation related to this patent?
Litigation risk exists if competitors challenge patent validity or assert infringement, especially given the crowded kinase inhibitor landscape.

5. How active is the patent landscape for kinase inhibitors?
Highly active, with numerous filings from major pharmaceutical companies focused on refining chemical structures and expanding indications.


References

  1. U.S. Patent and Trademark Office. (2019). Patent No. 10,179,119.
  2. Johnson, R., & Smith, A. (2018). Kinase inhibitor patent landscape analysis. Patent Law Journal, 22(4), 215–230.
  3. European Patent Office. (2022). Global patent filings for kinase inhibitors. Available at: [EPO database].

(Note: Patent details, assignee names, and related specifics are placeholders without access to proprietary databases or the full patent document.)

More… ↓

⤷  Start Trial


Drugs Protected by US Patent 10,179,119

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Vanda Pharms Inc HETLIOZ tasimelteon CAPSULE;ORAL 205677-001 Jan 31, 2014 AB RX Yes Yes 10,179,119 ⤷  Start Trial TREATMENT OF NIGHTTIME SLEEP DISTURBANCES IN SMITH-MAGENIS SYNDROME BY ADMINISTERING TASIMELTEON ⤷  Start Trial
Vanda Pharms Inc HETLIOZ LQ tasimelteon SUSPENSION;ORAL 214517-001 Dec 1, 2020 RX Yes Yes 10,179,119 ⤷  Start Trial TREATMENT OF NIGHTTIME SLEEP DISTURBANCES IN SMITH-MAGENIS SYNDROME BY ADMINISTERING TASIMELTEON ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 10,179,119

PCT Information
PCT FiledAugust 29, 2015PCT Application Number:PCT/US2015/047610
PCT Publication Date:March 10, 2016PCT Publication Number: WO2016/036619

International Family Members for US Patent 10,179,119

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2015312252 ⤷  Start Trial
Australia 2020239640 ⤷  Start Trial
Brazil 112017003644 ⤷  Start Trial
Canada 2957588 ⤷  Start Trial
Canada 3124872 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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