Last Updated: May 12, 2026

Patents Expiring in December 2044

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use
Avyxa Holdings	VYKOURA	leucovorin calcium	SOLUTION;INTRAMUSCULAR, INTRAVENOUS	220406-001	Feb 3, 2026		RX	Yes	Yes	⤷ Start Trial	⤷ Start Trial	Y
Avyxa Holdings	VYKOURA	leucovorin calcium	SOLUTION;INTRAMUSCULAR, INTRAVENOUS	220406-002	Feb 3, 2026		RX	Yes	Yes	⤷ Start Trial	⤷ Start Trial	Y
Avyxa Holdings	VYKOURA	leucovorin calcium	SOLUTION;INTRAMUSCULAR, INTRAVENOUS	220406-003	Feb 3, 2026		RX	Yes	Yes	⤷ Start Trial	⤷ Start Trial	Y
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use

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