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Serving hundreds of leading biopharmaceutical companies globally:

UBS
Queensland Health
US Department of Justice
US Army
Argus Health
Cipla
Citi
QuintilesIMS
Teva

Generated: July 17, 2018

DrugPatentWatch Database Preview

Details for Patent: 9,732,117

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Title:Steroids as agonists for FXR
Abstract: The invention relates to compounds of formula (I): ##STR00001## wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.
Inventor(s): Pellicciari; Roberto (Perugia, IT)
Assignee: Intercept Pharmaceuticals, Inc. (New York, NY)
Filing Date:Feb 05, 2016
Application Number:15/016,802
Claims:1. A pharmaceutically acceptable salt of compound of formula I: ##STR00007## wherein R is ethyl, or amino acid conjugate thereof, wherein the pharmaceutically acceptable salt can be selected from a group consisting of aluminum salt, calcium salt, lithium salt, magnesium salt, potassium salt, sodium salt, and zinc salt or N, N'-dibenzylethylenediamine salt, chlorprocaine salt, choline salt, diethanolamine salt, ethylendiamine salt, meglumine (N-methylglucamine) salt, and procaine salt.

2. The sodium salt of the compound of claim 1.

3. The lithium salt of the compound of claim 1.

4. The potassium salt of the compound of claim 1.

5. The calcium salt of the compound of claim 1.

6. The magnesium salt of the compound of claim 1.

7. The zinc salt of the compound of claim 1.

8. The choline salt of the compound of claim 1.

9. The diethanolamine salt of the compound of claim 1.

10. The N-methylglucamine salt of the compound of claim 1.

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Serving hundreds of leading biopharmaceutical companies globally:

Baxter
Merck
Boehringer Ingelheim
Medtronic
Queensland Health
Farmers Insurance
Teva
Dow
Cerilliant

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