Details for Patent: 9,663,517

Title:	Compositions and uses thereof
Abstract:	Provided are solid dispersions, solid molecular complexes, salts and crystalline polymorphs involving propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluor- o-phenyl}-amide.
Inventor(s):	Desai; Dipen (Whippany, NJ), Diodone; Ralph (Breisach, DE), Go; Zenaida (Clifton, NJ), Ibrahim; Prabha N. (Mountain View, CA), Iyer; Raman (Piscataway, NJ), Mair; Hans-Juergen (Loerrach, DE), Sandhu; Harpreet K. (West Orange, NJ), Shah; Navnit H. (Clifton, NJ), Visor; Gary (Castro Valley, CA), Wyttenbach; Nicole (Sissach, CH), Lauper; Stephan (Kaiseraugst, CH), Pudewell; Johannes (Oberwil, CH), Wierschem; Frank (Rheinfelden, CH)
Assignee:	Plexxikon Inc. (Berkeley, CA) Hoffman-La Roche Inc. (Nutley, NJ)
Filing Date:	Aug 19, 2016
Application Number:	15/241,773
Claims:	1. A crystalline polymorph Form 1 of Compound I: ##STR00003## that exhibits a powder x-ray diffraction pattern having characteristic peak locations of approximately 4.7, 9.4, 11.0, 12.5, and 15.4 degrees 2.theta.. 2. A crystalline polymorph according to claim 1, wherein said polymorph exhibits a powder x-ray diffraction pattern having characteristic peak locations of approximately 4.7, 9.4, 10.0, 11.0, 12.5, 14.2, 15.4, 18.6, and 22.2 degrees 2.theta.. 3. A crystalline polymorph according to claim 1, wherein said polymorph exhibits a powder x-ray diffraction pattern having characteristic peak locations of approximately 4.7, 9.4, 10.0, 11.0, 12.5, 14.2, 15.4, 16.1, 18.6, 19.0, 22.2 and 26.8 degrees 2.theta.. 4. A crystalline polymorph according to claim 1, wherein said polymorph exhibits a powder x-ray diffraction pattern substantially the same as the powder x-ray diffraction pattern of FIG. 1. 5. A purified form of the crystalline polymorph of claim 1.