Details for Patent: 9,555,191

Title:	Apparatus and methods for self-administration of vaccines and other medicaments
Abstract:	A medicament delivery device includes a housing, a medicament container disposed within the housing, an activation mechanism, a cover and an electronic circuit system. The activation mechanism includes an energy storage member configured to produce a force to deliver the dose of a medicament and/or vaccine. The cover is configured to receive at least a portion of the housing. The electronic circuit system is coupled to the housing such that a protrusion of the cover electrically isolates a battery from a portion of the electronic circuit system when the portion of the housing is received by the cover. The electronic circuit system is configured to be electrically coupled to the battery and to produce a recorded speech output when the portion of the housing is at least partially removed from the cover. The electronic circuit system configured to produce a signal when the activation mechanism is actuated.
Inventor(s):	Edwards; Eric S. (Moseley, VA), Edwards; Evan T. (Charlottesville, VA), Licata; Mark J. (Doswell, VA), Meyers; Paul F. (Fishers, IN), Weinzierl; David A. (Andover, MN)
Assignee:	kaleo, Inc. (Richmond, VA)
Filing Date:	Feb 16, 2016
Application Number:	15/044,337
Claims:	1. An apparatus, comprising: a container including a side wall defining a volume within which a medical injector can be disposed, a shape of the volume corresponding to a shape of the medical injector, the container including a lid movably coupled to the container, the lid configured to cover the volume when the lid is in a first position, the volume being exposed to allow access to the medical injector when the lid is in a second position; and an electronic circuit system coupled to the container, the electronic circuit system including a first switch, a second switch, a light output device, an audible output device, and a wireless communication module, the first switch configured to be actuated when the lid is moved from the first position to the second position, the second switch disposed within the volume such that the second switch extends from the side wall of the container, the medical injector in contact with a portion of the side wall of the container when the medical injector is within the volume, the second switch configured to move from a first state to a second state when the medical injector is removed from within the volume, the electronic circuit system configured to transmit, via the wireless communication module, a first wireless signal, the first wireless signal being a short-range radio frequency signal indicating that the container is within a transmission range of a remote computing device, the electronic circuit system configured to transmit, via the wireless communication module, a second wireless signal in response to the second switch moving from the first state to the second state, the second wireless signal being a short-range radio frequency signal indicating that the medical injector has been removed, the electronic circuit system configured to receive, via the wireless communication module, a third wireless signal and produce, in response to the third wireless signal, at least one of a visual output from the light output device or an audible output from the audible output device. 2. The apparatus of claim 1, wherein the medical injector is a single-use autoinjector, the shape of the single-use autoinjector being non-circular. 3. The apparatus of claim 1, wherein the lid is hingedly coupled to the container. 4. The apparatus of claim 1, wherein the wireless communication module includes at least one of a microprocessor, a transmitter, a receiver, a transceiver, or a radio chipset. 5. The apparatus of claim 1, wherein the second wireless signal includes information that, when received by the remote computing device, causes the remote computing device to send a location signal associated with a location associated with the container. 6. The apparatus of claim 1, wherein the second wireless signal includes information that, when received by the remote computing device, causes the remote computing device to output an instruction associated with the medical injector. 7. The apparatus of claim 1, wherein the electronic circuit system includes a temperature sensor, the electronic circuit system configured to transmit, via the wireless communication module, a fourth wireless signal, the fourth wireless signal being a short-range radio frequency signal indicating a temperature of the container. 8. The apparatus of claim 1, wherein at least one of the first wireless signal or the second wireless signal is encrypted. 9. The apparatus of claim 1, wherein the second switch is configured to be reversibly moved between the first state and the second state. 10. The apparatus of claim 1, wherein the second switch includes a biasing member configured to bias the second switch towards one of the first state or the second state. 11. The apparatus of claim 1, wherein the container defines the volume within which one and only one medical injector can be disposed, the apparatus further comprising: the medical injector, the medical injector being an autoinjector including an injector housing and a medicament container containing epinephrine disposed within the injector housing, the injector housing in contact with the portion of the side wall of the container when the medical injector is within the volume, a length of the portion of the side wall being greater than a length of the injector housing, the first wireless signal and the second wireless signal each being transmitted independently from an actuation of the autoinjector, at least one of the first wireless signal or the second wireless signal includes a unique identification associated with the autoinjector. 12. The apparatus of claim 11, wherein the second switch is configured to be reversibly moved between the first state and the second state. 13. An apparatus, comprising: a container defining a volume within which a medical injector can be disposed, a shape of the volume corresponding to a shape of the medical injector, the container including a lid movably coupled to the container, the lid configured to cover the volume when the lid is in a first position, the volume being exposed to allow access to the medical injector when the lid is in a second position; and an electronic circuit system coupled to the container, the electronic circuit system including a switch, a light output device, an audible output device, a temperature sensor, and a wireless communication module, the switch configured to move from a first state to a second state when the medical injector is removed from the volume, the electronic circuit system configured to transmit, via the wireless communication module, a first wireless signal, the first wireless signal being a short-range radio frequency signal indicating that the container is within a transmission range of a remote computing device, the electronic circuit system configured to transmit, via the wireless communication module, a second wireless signal in response to the switch moving from the first state to the second state, the second wireless signal being a short-range radio frequency signal indicating that the medical injector has been removed, the second wireless signal including information that, when received by the remote computing device, causes the remote computing device to output an instruction associated with the medical injector, the electronic circuit system configured to transmit, via the wireless communication module, a third wireless signal, the third wireless signal being a short-range radio frequency signal indicating a temperature of the container. 14. The apparatus of claim 13, wherein the medical injector is a single-use autoinjector having a distal end portion, a proximal end portion, and defining a longitudinal axis therebetween, the shape of the single-use autoinjector in a plane normal to the longitudinal axis being non-circular. 15. The apparatus of claim 14, wherein the volume defined by the container is elongated such that when the lid is in the second position, the single-use autoinjector can be removed from the volume by moving the single-use autoinjector along the longitudinal axis such that the proximal end portion is removed from the volume before the distal end portion is removed from the volume. 16. The apparatus of claim 13, wherein: the medical injector is a single-use autoinjector; and the container defines a recess configured to receive a protrusion of the single-use autoinjector to limit movement of the single-use autoinjector when the single-use autoinjector is disposed within the volume of the container. 17. The apparatus of claim 13, wherein the second wireless signal includes information that, when received by the remote computing device, causes the remote computing device to send a location signal associated with a location associated with the container. 18. The apparatus of claim 13, wherein: the switch is a first switch; and the electronic circuit system includes a circuit board and a second switch coupled to the circuit board, a portion of the lid configured to engage the second switch when the lid is moved between the first position and the second position to actuate the second switch, the electronic circuit system configured to produce an electronic output when the second switch is actuated. 19. An apparatus, comprising: an autoinjector including a housing and a medicament container disposed within the housing; a compliance monitor housing including a side wall defining a volume within which the autoinjector can be disposed, the compliance monitor housing including a lid configured to retain the autoinjector within the volume; and an electronic circuit system coupled to the compliance monitor housing, the electronic circuit system including a first switch, a second switch, a light output device, an audible output device, and a wireless communication module, the first switch configured to be actuated when the lid is opened to expose the volume, the second switch coupled to the side wall of the compliance monitor housing, the autoinjector in contact with a portion of the side wall of the compliance monitor housing when the autoinjector is within the volume, the second switch configured to move from a first state to a second state when the autoinjector is removed from the compliance monitor housing, the electronic circuit system configured to transmit, via the wireless communication module, a first wireless signal, the first wireless signal being a short-range radio frequency signal indicating that the compliance monitor housing is within a transmission range of a remote computing device, the electronic circuit system configured to transmit, via the wireless communication module, a second wireless signal in response to the second switch moving from the first state to the second state, the second wireless signal being a short-range radio frequency signal, the electronic circuit system configured to receive, via the wireless communication module, a third wireless signal and produce, in response to the third wireless signal, at least one of a visual output from the light output device or an audible output from the audible output device. 20. The apparatus of claim 19, wherein the wireless communication module includes at least one of a microprocessor, a transmitter, a receiver, a transceiver, or a radio chipset. 21. The apparatus of claim 19, wherein the second wireless signal includes information that, when received by the remote computing device, causes the remote computing device to send a location signal associated with a location associated with the compliance monitor housing. 22. The apparatus of claim 19, wherein the second wireless signal includes information that, when received by the remote computing device, causes the remote computing device to output an instruction associated with the autoinjector. 23. The apparatus of claim 19, wherein the electronic circuit system includes a temperature sensor, the electronic circuit system configured to transmit, via the wireless communication module, a fourth wireless signal, the fourth wireless signal being a short-range radio frequency signal indicating a temperature of the compliance monitor housing. 24. The apparatus of claim 19, wherein the second switch extends from the sidewall of the compliance monitor housing, the second switch including a biasing member configured to bias the second switch towards one of the first state or the second state.