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Title:Nucleoside phosphoramidate prodrugs
Abstract: Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure: ##STR00001## Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I.
Inventor(s): Du; Jinfa (Redwood City, CA), Nagarathnam; Dhanapalan (Bethany, CT), Sofia; Michael Joseph (Doylestown, PA), Wang; Peiyuan (Foster City, CA)
Assignee: Gilead Pharmasset LLC (Foster City, CA)
Filing Date:Apr 16, 2014
Application Number:14/254,737
Claims:1. cited by applicant .
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Attorney, Agent or Firm: Sheppard Mullin Richter & Hampton LLP
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