Details for Patent: 8,101,630
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Title: | Extended release opioid abuse deterrent compositions and methods of making same |
Abstract: | This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix. |
Inventor(s): | Kumar; Vijai (Morris Plains, NJ), Dixon; David (Woodside, NY), Tewari; Divya (Suffern, NY), Wadgaonkar; Dilip B. (Suffern, NY) |
Assignee: | Acura Pharmaceuticals, Inc. (Palantine, IL) |
Filing Date: | Mar 30, 2009 |
Application Number: | 12/383,906 |
Claims: | 1. An extended release abuse deterrent dosage form comprising: a. a core matrix comprising a blended mixture of: (a) PEO having a molecular weight of from about 300,000 to about 5,000,000; (b) magnesium stearate; and (c) oxycodone or a pharmaceutically acceptable salt thereof; wherein the matrix is heated to melt at least a portion of the PEO included in the matrix; and b. PEG applied onto the core matrix; wherein the dosage form provides extended release of the drug. |