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|Title:||Extended release opioid abuse deterrent compositions and methods of making same|
|Abstract:||This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.|
|Inventor(s):||Kumar; Vijai (Morris Plains, NJ), Dixon; David (Woodside, NY), Tewari; Divya (Suffern, NY), Wadgaonkar; Dilip B. (Suffern, NY)|
|Assignee:||Acura Pharmaceuticals, Inc. (Palantine, IL)|
|Filing Date:||Mar 30, 2009|
|Claims:||1. An extended release abuse deterrent dosage form comprising: a. a core matrix comprising a blended mixture of: (a) PEO having a molecular weight of from about 300,000 to about 5,000,000; (b) magnesium stearate; and (c) oxycodone or a pharmaceutically acceptable salt thereof; wherein the matrix is heated to melt at least a portion of the PEO included in the matrix; and b. PEG applied onto the core matrix; wherein the dosage form provides extended release of the drug.|
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