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Details for Patent: 7,888,317

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Details for Patent: 7,888,317

Title:Glucagon-like peptide-2 and its therapeutic use
Abstract: Glucagon-like peptide 2, a product of glucagon gene expression, and analogs of glucagon-like peptide 2, have been identified as gastrointestinal tissue growth factors. Their effects on the growth of small bowel and pancreatic islets are described. Their formulation as a pharmaceutical, and their therapeutic use in treating disorders of the bowel, are described.
Inventor(s): Drucker; Daniel J. (Toronto, CA)
Assignee: NPS Pharmaceuticals, Inc. (Bedminster, NJ)
Filing Date:Jan 05, 2006
Application Number:11/325,527
Claims:1. A method for promoting an increase of the crypt plus villus height in a patient in need thereof, comprising the step of delivering to the patient a pharmaceutical composition comprising a mammalian GLP-2 and a pharmaceutically acceptable carrier.

2. The method for promoting an increase of the crypt plus villus height in a patient in need thereof according to claim 1, wherein the peptide is a mammalian GLP-2.

3. The method for promoting an increase of the crypt plus villus height in a patient in need thereof according to claim 1, wherein the mammalian GLP-2 is human GLP-2 (SEQ ID NO: 4).

4. The method for promoting an increase of the crypt plus villus height in a patient in need thereof according to claim 1, wherein the mammalian GLP-2 is rat GLP-2 (SEQ ID NO: 3).
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