.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Details for Patent: 7,427,600

« Back to Dashboard

Details for Patent: 7,427,600

Title:Active agent delivery systems and methods for protecting and administering active agents
Abstract: The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.
Inventor(s): Mickle; Travis (Charlottesville, VA), Krishnan; Suma (Blacksburg, VA), Moncrief; James Scott (Christiansburg, VA), Lauderback; Christopher (Blacksburg, VA), Piccariello; Thomas (Blacksburg, VA), Kirk; Randal (Radford, VA)
Assignee: Shire LLC (Florence, KY)
Filing Date:Aug 23, 2004
Application Number:10/923,088
Claims:1. A method of treating inflammatory bowel disease comprising administering to a patient in need thereof an effective amount of a compound consisting of mesalamine covalently attached to a single amino acid selected from Valine, Alanine, Asparagine, Isoleucine, Proline, Lysine, Cysteine, Glutamine, Histidine, Methionine, Phenylalanine, Serine, Threonine, Tryptophan and Tyrosine or a pharmaceutically acceptable salt thereof.

2. A compound consisting of mesalamine covalently attached to a single amino acid wherein said single amino acid is selected from Valine, Alanine, Asparagine, Isoleucine, Proline, Lysine, Cysteine, Glutamine, Histidine, Methionine, Phenylalanine, Serine, Threonine, Tryptophan and Tyrosine or a pharmaceutically acceptable salt thereof.

3. The compound of claim 2, wherein the amino acid is Valine.

4. A pharmaceutical composition comprising: a compound consisting of mesalamine covalently attached to a single amino acid selected from Valine, Alanine, Asparagine, Isoleucine, Proline, Lysine, Cysteine, Glutamine, Histidine, Methionine, Phenylalanine, Serine, Threonine, Tryptophan and Tyrosine or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable excipient.

5. The pharmaceutical composition of claim 4, wherein said composition is an oral dosage form.

6. The pharmaceutical composition of claim 4, wherein the compound is mesalamine covalently attached to Valine.

7. The method of claim 1, wherein the compound is mesalamine covalently attached to Valine.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc