Details for Patent: 7,060,730

Title:	Rapidly absorbed liquid compositions
Abstract:	The present invention provides a method which provides for a faster absorption of pharmaceutically acceptable amines. The method provides a pharmaceutically acceptable amine in combination with a non-steroidal anti-inflammatory drug in a liquid form. A preferred embodiment employs pseudoephedrine and ibuprofen.
Inventor(s):	Gelotte; Cathy Klech (North Wales, PA), Hills; Joanna F. (Glenside, PA), Pendley, II; Charles E. (Abington, PA), Shah; Manoj N. (Norristown, PA)
Assignee:
Filing Date:	Jun 26, 2003
Application Number:	10/608,170
Claims:	1. A method for enhancing the absorption rate of a pharmaceutically acceptable amine into the blood of a human child comprising administering a stable suspension comprising (i) a phamnacologically effective dosage of a pharmaceutically acceptable amine and (ii) an effective amount of ibuprofen. 2. The method of claim 1 wherein the amine is pseudoephedrine. 3. The method of claim 1 wherein the enhanced absorption is indicated by AUC 1 H (early drug exposure) that is at least about 10% higher than the early drug exposure of the same amine from a single-ingredient liquid. 4. method of claim 1 wherein the enhanced absorption is indicated by AUC 2 H (early drug exposure) that is at least about 10% higher than the early drug exposure of the same amine from a single-ingredient liquid. 5. The method of claim 1 wherein the enhanced absorption is indicated by a C MAX (maximum or peak concentration) that is at least about 10% greater than the C MAX of the same amine from a single-ingredient liquid. 6. The method of claim 1 wherein the amine is provided in a range from about 15 mg to about 60 mg per dosage unit. 7. The method of claim 1 wherein the ibuprofen is provided in an amount of from about 40 mg to about 800 mg per dosage unit. 8. The method of claim 6 wherein the ibuprofen is provided in an amount of from about 40 mg to about 800 mg per dosage unit. 9. The method of claim 1 wherein the amine is provided at about 15 milligrams per 5 mL and the ibuprofen is provided at about 100 milligrams per 5 mL.