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Serving leading biopharmaceutical companies globally:

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Generated: November 18, 2017

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Title: High affinity vascular endothelial growth factor (VEGF) receptor nucleic acid ligands and inhibitors
Abstract:Methods are described for the identification and preparation of high-affinity nucleic acid ligands to a VEGF receptor. Included in the invention are specific RNA ligands to a VEGF receptor identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of a VEGF receptor with VEGF.
Inventor(s): Janjic; Nebojsa (Boulder, CO), Gold; Larry (Boulder, CO)
Assignee: Gilead Sciences, Inc. (Foster City, CA)
Filing Date:Jul 29, 1999
Application Number:09/364,540
Claims:1. A purified and isolated non-naturally occurring RNA nucleic acid ligand to VEGFR2 wherein said ligand is selected from the group consisting of the sequences set forth in SEQ ID NO:2 to SEQ ID NO:36.
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Serving leading biopharmaceutical companies globally:

McKesson
QuintilesIMS
Cipla
Citi
Accenture
Express Scripts
Argus Health
Dow
Farmers Insurance
Chinese Patent Office

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