Generated: April 25, 2017
|Title:||Buccal, polar and non-polar spray or capsule|
|Abstract:||Buccal aerosol sprays or capsule using polar and non-polar solvent have now been developed which provide biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal polar compositions of the invention comprises formulation I: polar solvent 37-98.58%, active compound 0.005-55%, optionally containing flavoring agent 0.1-10%.|
|Inventor(s):||Dugger, III.; Harry A. (Flemington, NJ)|
|Assignee:||NovaDel Pharma Inc. (Flemington, NJ)|
|Filing Date:||Mar 18, 2002|
|Claims:||1. A propellant free pump spray composition comprising a pharmacologically acceptable polar solvent in an amount of 75-85 weight percent of the total composition, cyclosporin in an amount of 15-25 weight percent of the total composition, and flavoring agent in an amount of 0.1-5 weight percent of the total composition wherein said composition is adapted for transmucosal administration of the cyclosporin through the oral mucosa. |
2. A propellant free pump spray composition comprising a pharmacologically acceptable polar solvent in an amount of 19-90 weight percent of the total composition, ondansetron hydrochloride in an amount of 2.5-15 weight percent of the total composition, and flavoring agent in an amount of 0.1-10 weight percent of the total composition wherein said composition is adapted for transmucosal administration of the ondansetron hydrochloride through the oral mucosa.
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