Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||High affinity nucleic acid ligands of complement system proteins|
|Abstract:||Methods are described for the identification and preparation of high-affinity Nucleic Acid Ligands to Complement System Proteins. Methods are described for the identification and preparation of high affinity Nucleic Acid Ligands to Complement System Proteins C1q, C3 and C5. Included in the invention arc specific RNA ligands to C1q, C3 and C5 identified by the SELEX method.|
|Inventor(s):||Biesecker; Gregory (Boulder, CO), Gold; Larry (Boulder, CO)|
|Assignee:||NeXstar Pharmaceuticals, Inc. (Boulder, CO)|
|Filing Date:||Feb 12, 1998|
|Claims:||1. A purified and non-naturally occurring RNA Ligand to C1q, wherein said ligand is selected from the group consisting of SEQ ID NOS:84-155. |
2. A purified and non-naturally occurring RNA Ligand to C3, wherein said ligand is selected from the group consisting of SEQ ID NOS:21-46.
3. A purified and non naturally occurring RNA Ligand to C5, wherein said ligand is selected from the group consisting of SEQ ID NOS:47-83.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.