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Generated: November 22, 2017

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Claims for Patent: 7,915,269

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Claims for Patent: 7,915,269

Title:Methods for concomitant administration of colchicine and a second active agent
Abstract:Methods for concomitant administration of colchicine together with one or more second active agents, e.g., ketoconazole and ritonavir, are disclosed. Such methods reduce the dangers commonly associated with such concomitant administration and provide additional benefits. Methods of notifying health care practitioners and patients regarding appropriate dosing for concomitant administration of colchicine together with second active agents are also provided.
Inventor(s): Davis; Matthew W. (Erwinna, PA)
Assignee: AR Holding Company, Inc. (Wilmington, DE)
Application Number:12/858,667
Patent Claims: 1. A method of treating a patient in need of treatment for gout flares with colchicine, comprising orally administering to the patient in need of treatment for gout flares, an adjusted daily dosage amount of colchicine wherein the patient is receiving concomitant administration of 200 mg per day of ritonavir, wherein the adjusted daily dosage amount of colchicine is 25% to 50% of an intended daily dosage amount in the absence of concomitant ritonavir, wherein the intended daily dosage amount in the absence of concomitant ritonavir is 1.2 mg at the first sign of flare, followed by 0.6 mg one hour later, dose to be repeated no earlier than 3 days.
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Serving leading biopharmaceutical companies globally:

McKinsey
Mallinckrodt
Teva
US Department of Justice
Argus Health
Chinese Patent Office
Fish and Richardson
Farmers Insurance
Cerilliant
Accenture

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