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Serving hundreds of leading biopharmaceutical companies globally:

Julphar
Chinese Patent Office
AstraZeneca
Daiichi Sankyo
Colorcon
Queensland Health
Express Scripts
Citi
Merck

Generated: June 23, 2018

DrugPatentWatch Database Preview

Claims for Patent: 7,820,681

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Summary for Patent: 7,820,681
Title:Methods for concomitant administration of colchicine and a second active agent
Abstract:Methods for concomitant administration of colchicine together with one or more second active agents, e.g., ketoconazole and ritonavir, are disclosed. Such methods reduce the dangers commonly associated with such concomitant administration and provide additional benefits. Methods of notifying health care practitioners and patients regarding appropriate dosing for concomitant administration of colchicine together with second active agents are also provided.
Inventor(s): Davis; Matthew W. (Erwinna, PA)
Assignee: Mutual Pharmaceutical Company, Inc. (Philadelphia, PA)
Application Number:12/372,046
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,820,681
Patent Claims: 1. A method of treating a patient in need of treatment for the prophylaxis of gout flares with colchicine, comprising orally administering to the patient in need of treatment for the prophylaxis of gout flares, an adjusted daily dosage amount of colchicine to the patient who is receiving concomitant administration of 200 mg per day of ritonavir, wherein the adjusted daily dosage amount of colchicine is 25% to 50% of 0.6 mg twice per day or 0.6 mg once per day, which is an amount of colchicine suitable for the patient if the patient were not receiving concomitant ritonavir.

2. The method of claim 1, further comprising carefully monitoring the individual for potential toxicity.

3. The method of claim 1, wherein the adjusted daily dosage amount of colchicine is 25% of an intended daily dosage amount of colchicine.

4. The method of claim 1, wherein the adjusted daily dosage amount of colchicine is 50% of an intended daily dosage amount of colchicine.

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Serving hundreds of leading biopharmaceutical companies globally:

QuintilesIMS
Cerilliant
Colorcon
AstraZeneca
Chinese Patent Office
US Department of Justice
Dow
US Army
Fuji

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