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Claims for Patent: 6,211,229

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Claims for Patent: 6,211,229

Title: Treatment of transient and short term insomnia
Abstract:The invention is directed to a method for the treatment of a patient suffering from transient or short term insomnia. The claimed method comprises the administration of a compound selected from the group consisting of the pharmaceutically acceptable forms of doxepin, amitriptyline, trimipramine, trazodone and mixtures thereof in dosages ranging from about 0.5 to about 20.0 milligrams.
Inventor(s): Kavey; Neil B. (Chappaqua, NY)
Assignee:
Application Number:09/506,348
Patent Claims: 1. A method for the treatment of a patient suffering from non-chronic insomnia of from one night to about three weeks in duration comprising administering to said patient a compound selected from the group consisting of the pharmaceutically acceptable forms of doxepin, amitriptyline, trimipramine, trazodone and mixtures thereof in a daily dosage ranging from about 0.5 to about 20 milligrams.

2. The method of claim 1 wherein the pharmaceutically acceptable form of doxepin, amitriptyline, trazodone and mixtures thereof are the hydrochloride salts thereof and the pharmaceutically acceptable form of trimipramine is the maleate salt.

3. The method of claim 1 wherein the dosage of doxepin, amitriptyline, trimipramine and mixtures thereof is about 10 milligrams or less.

4. The method of claim 1 wherein the dosage is about 5 milligrams or less.

5. The method of claim 1 wherein the compound is doxepin hydrochloride.

6. The method of claim 5 wherein the dosage is about 10 milligrams or less.

7. The method of claim 5 wherein the dosage is about 5 milligrams or less.

8. The method of claim 1 wherein the compound is amitriptyline.

9. The method of claim 8 wherein the dosage is about 10 milligrams or less.

10. The method of claim 8 wherein the dosage is about 5 milligrams or less.

11. The method of claim 1 wherein the compound is trimipramine.

12. The method of claim 11 wherein the dosage is about 10 milligrams or less.

13. The method of claim 11 wherein the dosage is about 5 milligrams or less.

14. The method of claim 1 wherein the compound is trazodone.

15. The method of claim 14 wherein the dosage of trazodone ranges from about 5 to about 15 milligrams.

16. The method of claim 1 wherein non-chronic insomnia is onset insomnia.

17. The method of claim 16 wherein the dosage of doxepin, amitriptyline, trimipramine and mixtures thereof is about 10 milligrams or less.

18. The method of claim 17 wherein the dosage is about 5 milligrams or less.

19. The method of claim 16 wherein the compound is doxepin hydrochloride.

20. The method of claim 19 wherein the dosage is about 10 milligrams or less.

21. The method of claim 19 wherein the dosage is about 5 milligrams or less.

22. The method of claim 16 wherein the dosage of trazodone is about 15 milligrams or less.

23. The method of claim 22 wherein the dosage is about 10 milligrams or less.

24. The method of claim 1 wherein non-chronic insomnia is maintenance insomnia.

25. The method of claim 24 wherein the dosage of doxepin, amitriptyline, trimipramine and mixtures thereof is about 10 milligrams or less.

26. The method of claim 25 wherein the dosage is about 5 milligrams or less.

27. The method of claim 25 wherein the compound is doxepin hydrochloride.

28. The method of claim 27 wherein the dosage is about 10 milligrams or less.

29. The method of claim 27 wherein the dosage is about 5 milligrams or less.

30. The method of claim 24 wherein the dosage of trazodone is about 15 milligrams or less.

31. The method of claim 30 wherein the dosage is about 10 milligrams or less.
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