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Generated: September 19, 2017

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Title: Seals for use in an aerosol delivery device
Abstract:A device for delivering an aerosol, comprising: a casing member, a valve stem, and a diaphragm. The diaphragm is made of an ethylene-propylene-diene rubber ("EPDM") and is stable to dimensional change when exposed to 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoroethane.
Inventor(s): Kwon; Oh-Seung (Woodbury, MN)
Assignee: Minnesota Mining & Manufacturing Co. (St. Paul, MN)
Application Number:08/397,546
Patent Claims: 1. A device for delivering an aerosol, comprising: a valve stem, a diaphragm comprising an ethylene-propylene-diene rubber free of silicone adhesive agents and having walls defining a diaphragm aperture, and a casing member having walls defining a formulation chamber and a casing aperture, wherein the valve stem passes through the diaphragm aperture and the casing aperture and is in slidable sealing engagement with the diaphragm aperture, and wherein the diaphragm is in sealing engagement with the casing member, the device having contained in the formulation chamber thereof a medicinal aerosol formulation wherein the medicinal aerosol formulation comprises 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoropropane.

2. A device according to claim 1 wherein the diaphragm is stable to dimensional change when exposed to the medicinal aerosol formulation.

3. A device according to claim 1, wherein the ethylene-propylene-diene rubber is the only polymer component of the diaphragm.

4. A device according to claim 1, wherein the ethylene-propylene-diene rubber is present in the form of particles dispersed in a continuous thermoplastic matrix.

5. A device according to claim 4, wherein the thermoplastic matrix comprises polypropylene or polyethylene.

6. A device according to claim 2, wherein the ethylene-propylene-diene rubber is the only polymer component of the diaphragm.

7. A device according to claim 2, wherein the ethylene-propylene-diene rubber is present in the form of particles dispersed in a continuous thermoplastic matrix.

8. A device according to claim 7, wherein the thermoplastic matrix comprises polypropylene or polyethylene.
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Serving 500+ biopharmaceutical companies globally:

Cerilliant
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Queensland Health
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Boehringer Ingelheim
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