Claims for Patent: 4,880,636

Summary for Patent: 4,880,636

Title:	Film coated tablet of ranitidine HCl
Abstract:	This invention relates to an improved polymeric film coating for a ranitidine Hydrocholride (HCl) tablet in which the plasticizer triacetin had been added to the polymeric film coating medium. A tablet of this invention has been found to have great stability than a tablet coating with a polymeric film which does not contain triacetin.
Inventor(s):	Franz; Robert M. (Raleigh, NC)
Assignee:
Application Number:	07/194,427
Patent Claims:	1. A ranitidine HCl tablet coated with a polymeric film comprising; hydroxypropyl methylcellulose (HPMC), 5% to 25% (based on the weight of said HPMC) triacetin and optionally 5% to 65% (based on the weight of said HPMC) colorant or opacifying agent. 2. A tablet of claim 1 wherein the polymeric coat is in the range of 2.1 to 5.0 parts by weight per 100 parts by weight of the tablet. 3. A tablet of claim 1 wherein the polymeric coat is in the range of 3.5 to 4.5 parts by weight per 100 parts by weight of the tablet. 4. A tablet of claim 1 wherein the polymeric film coating also contains one or more opacifying agents. 5. A tablet of claim 1 wherein the polymeric film coating also contains one or more colorants. 6. A tablet of claim 1 wherein the polymeric film coating also contains one or more colorants and one or more opacifying agents.