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Claims for Patent: 4,880,636

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Claims for Patent: 4,880,636

Title: Film coated tablet of ranitidine HCl
Abstract:This invention relates to an improved polymeric film coating for a ranitidine Hydrocholride (HCl) tablet in which the plasticizer triacetin had been added to the polymeric film coating medium. A tablet of this invention has been found to have great stability than a tablet coating with a polymeric film which does not contain triacetin.
Inventor(s): Franz; Robert M. (Raleigh, NC)
Assignee:
Application Number:07/194,427
Patent Claims: 1. A ranitidine HCl tablet coated with a polymeric film comprising; hydroxypropyl methylcellulose (HPMC), 5% to 25% (based on the weight of said HPMC) triacetin and optionally 5% to 65% (based on the weight of said HPMC) colorant or opacifying agent.

2. A tablet of claim 1 wherein the polymeric coat is in the range of 2.1 to 5.0 parts by weight per 100 parts by weight of the tablet.

3. A tablet of claim 1 wherein the polymeric coat is in the range of 3.5 to 4.5 parts by weight per 100 parts by weight of the tablet.

4. A tablet of claim 1 wherein the polymeric film coating also contains one or more opacifying agents.

5. A tablet of claim 1 wherein the polymeric film coating also contains one or more colorants.

6. A tablet of claim 1 wherein the polymeric film coating also contains one or more colorants and one or more opacifying agents.
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