You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 26, 2024

Claims for Patent: 4,605,671

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 4,605,671

Title:	Parenteral formulation
Abstract:	Ready-to-use parenteral formulations of Dezocine containing from about 0.2 to about 2.0 percent wt/vol. Dezocine; about 30 to about 45 percent wt/vol. propylene glycol; about 0.5 to about 2.0 percent wt/vol. lactic acid buffered with a pharmaceutically acceptable base to a pH of from about 3.5 to about 5.0 and 0 to 0.02 percent wt/vol. sodium metabisulfite, in water for injection.
Inventor(s):	DeYoung; Joyce L. (Wayne, PA)
Assignee:	American Home Products Corporation (New York, NY)
Application Number:	06/757,992
Patent Claims:	1. A parenterally acceptable, aqueous composition consisting essentially of from 0.2 to about 2.0 percent weight/volume of (-)-13.beta.-amino-5,6,7,8,9,10,11,12-octahydro-5.alpha.-methyl-5,11-metha nobenzocyclodecen-3-ol; from about 30 to about 45 percent weight/volume propylene glycol; from about 0.5 to about 2.0 percent weight/volume of lactic acid buffered with a pharmaceutically acceptable base to afford a pH of from about 3.5 to about 5.0; and from 0 to 0.02 percent weight/volume of sodium or potassium metabisulfite, in water for injection. 2. A composition of claim 1 which contains about 0.0075 to about 0.015 weight/volume sodium metabisulfite. 3. A composition of claim 1 in which said pharmaceutically acceptable base is sodium hydroxide. 4. A composition of claim 1 consisting essentially of about 0.5 percent weight/volume (-)-13.beta.-amino-5,6,7,8,9,10,11,12-octahydro-5.alpha.-methyl-5,11-metha nobenzocyclodecen-3-ol; about 0.015 percent weight/volume sodium metabisulfite; about 31 percent weight/volume propylene glycol; about 0.6 percent weight/volume lactic acid; sufficient sodium hydroxide to afford a pH of about 4.0 and sufficient water for injection to afford an aqueous solution containing the recited ingredient concentration. 5. A composition of claim 1 consisting essentially of about 1.0 percent weight/volume (-)-13.beta.-amino-5,6,7,8,9,10,11,12-octahydro-5.alpha.-methyl-5,11-metha nobenzocyclodecen-3-ol; about 0.015 percent weight/volume sodium metabisulfite; about 31 percent weight/volume propylene glycol; about 0.8 percent weight/volume lactic acid; sufficient sodium hydroxide to afford a pH of about 4.0 and sufficient water for injection to afford an aqueous solution containing the recited ingredient concentration. 6. A composition of claim 1 consisting essentially of about 1.5 percent weight/volume (-)-13.beta.-amino-5,6,7,8,9,10,11,12-octahydro-5.alpha.-methyl-5,11-metha nobenzocyclodecen-3-ol; about 0.0075 percent weight/volume sodium metabisulfite; about 31 percent weight/volume propylene glycol; about 1.0 percent weight/volume lactic acid; sufficient sodium hydroxide to afford a pH of about 4.0 and sufficient water for injection to afford an aqueous solution containing the recited ingredient concentration.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.